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Phosphoaminophosphonic acid guanylate ester
go.drugbank.com/drugs/DB02082ExperimentalA non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+.
(1R,2S)-2-Phenylcyclopropanaminium
go.drugbank.com/drugs/DB02665ExperimentalThis monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders.
Zebularine
go.drugbank.com/drugs/DB03068ExperimentalAlso shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.
Fosclevudine alafenamide
go.drugbank.com/drugs/DB19113InvestigationalFosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With
Synonyms: L-alanine, n-((s)-hydroxyphenoxyphosphinyl)-, 1-methylethyl ester, 5'-ester with 1-(2-deoxy-2-fluoro-.beta.-l-arabinofuranosyl)-5-methyl-2,4(1h,3h)-pyrimidinedioneSimmerafil
go.drugbank.com/drugs/DB22792InvestigationalSimmerafil is under investigation in clinical trial NCT06301854 (Long-term Safety of TPN171H Tablet in Erectile Dysfunction.).
DCFBC F-18
go.drugbank.com/drugs/DB14772InvestigationalDCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Modotuximab
go.drugbank.com/drugs/DB14827InvestigationalModotuximab is under investigation in clinical trial NCT03549338 (Sym004 Versus Futuximab or Modotuximab in Patients With mCRC).
Narnatumab
go.drugbank.com/drugs/DB14964InvestigationalNarnatumab is under investigation in clinical trial NCT01119456 (A Study of IMC-RON8 in Advanced Solid Tumors).
BI 44370 TA
go.drugbank.com/drugs/DB16037InvestigationalBI 44370 TA is under investigation in clinical trial NCT00751803 (BI 44370 TA in Acute Migraine Attack).
DU125530
go.drugbank.com/drugs/DB16040InvestigationalDU125530 is under investigation in clinical trial NCT01119430 (Fluoxetine Versus Fluoxetine Plus DU125530 in Major Depressive Disorder).