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Somatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigationalIt has an identical primary protein structure to endogenous human growth hormone.[A228188] Recombinant HGH has been commercially available since 1985 after its development by Genentech. … [A228183] Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and lipid
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InducersProducts: OMNITROPE® SOLUCION INYECTABLE EN CARTUCHO DE 10 MG / 1.5 ML, SAIZEN 4 IU FLAKON, 1 ADETFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalFumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingProducts: ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, ANESED-R 0.5 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADETManganese gluconate
go.drugbank.com/drugs/DB11141ApprovedManganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. … Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement.
Synonyms: Manganese D-gluconateMixtures: Cal-mag Plus K, Mn and Zn Caplets, Children's Chew Multi & Min TabDosulepin
go.drugbank.com/drugs/DB09167ApprovedInvestigationalDosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South … Dosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits anticholinergic, antihistamine and central sedative properties [L882].
Synonyms: (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine, 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepinCategories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 CYP1A2 InhibitorsEdoxudine
go.drugbank.com/drugs/DB13421ApprovedWithdrawnThe obtained product is an antiviral ointment.[L2407] The activity of edoxudine against herpes simplex virus was first recognized in 1967. … Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2.
Synonyms: 2'-Deoxy-5-ethyluridine, 5-Ethyl-2'-deoxyuridineCategories: Heterocyclic Compounds, 1-RingDomvanalimab
go.drugbank.com/drugs/DB18848InvestigationalDomvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Synonyms: Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus musculus monoclonal ab154 .gamma.1-chain), disulfide with human-mus musculus monoclonal ab154 .kappaAtosiban
go.drugbank.com/drugs/DB09059ApprovedInvestigationalAtosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor. … Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.
Products: EVERPREM® SOLUCIÓN PARA INFUSIÓN 6.75 MG/0.9 ML, TRACTOCILE 37.5 MG/ 5 ML CONCENTRADO PARA SOLUCION POR INFUSIONPhenylalanine
go.drugbank.com/drugs/DB00120ApprovedInvestigationalNutraceuticalPhenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and [thyroxine].
Synonyms: (S)-2-Amino-3-phenylpropionic acid, 3-phenyl-L-alanineMixtures: 4.25%travasol Amino Acid InJ.W.elecw.5%dex., 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.Gelatin
go.drugbank.com/drugs/DB11242ApprovedInvestigationalVet approvedWithdrawnAn increasing number of novel applications have been found for collagen and gelatin.[A32426] Gelatin is generally recognized as safe (GRAS) by the FDA to be a non-hazardous food or food ingredient. … alternative raw substances have recently garnered attention from both researchers and the industry not only because they overcome religious concerns shared by both Jews and Muslims but also because they may
Mixtures: GELOFUSINE® ISO 4%Products: INFUSOL SG (SUCCINYLATED GELATIN (Bovine) INTRAVENOUS INFUSION 4% w/v), GELAFUNDIN 4Ivabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigationalTherefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing … Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate
Synonyms: 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-oneMixtures: CARIVALAN 25/5, CARIVALAN 6.25/5