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Displaying results 771 - 780 of 6076 in total
  1. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547].

  2. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [L56091, A257419] Leucovorin has been explored experimentally for autism spectrum disorder.[A275451, A275452] … [L56092, A257419] Unlike folic acid, leucovorin does not require the enzyme dihydrofolate reductase (DHFR) for activation, allowing it to function even when DHFR is inhibited by drugs like methotrexate

    Categories: Detoxifying Agents for Antineoplastic Treatment
  3. Drug

    Tyrosine

    go.drugbank.com/drugs/DB00135
    ApprovedInvestigationalNutraceutical

    Tyrosine is a non-essential amino acid. In animals it is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.

    Mixtures: KABIVEN EMULSION FOR INFUSION, OLIMEL N7E, emulsion for infusion
  4. Drug

    Potassium gluconate

    go.drugbank.com/drugs/DB13620
    Approved

    Potassium gluconate is a salt of DB01345 and is classified as a food additive by the FDA . It is also used as a potassium supplement . Potassium is an essential nutrient. It is the most abundant cation in the intracellular fluid, where i...

    Mixtures: Multivitamins and Minerals for Young Men, Multivitamins and Minerals for Young Women
  5. Drug

    Zinc citrate

    go.drugbank.com/drugs/DB11154
    ApprovedInvestigational

    Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral a...

    Mixtures: For Men, Multivitamins and Minerals for Young MenCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  6. Drug

    Zanidatamab

    go.drugbank.com/drugs/DB15471
    ApprovedInvestigational

    [A264718] In November 2024, the FDA granted an accelerated approval for zanidatamab for use in previously treated unresectable or metastatic HER2-positive biliary tract cancers.[L51908,L51903] … [A264718] It has been investigated for the treatment of HER2-positive solid tumors, including gastroesophageal, colorectal, and biliary tract cancers.

  7. Drug

    Vibegron

    go.drugbank.com/drugs/DB14895
    ApprovedInvestigational

    On December 23, 2020, vibegron was approved for the same indication in adults. It is available as oral tablets under the market name GEMTESA. … [L28310] Vibegron is the second beta-3 adrenergic agonist approved for the treatment of overactive bladder following [mirabegron], which was approved in 2012.

    Categories: Drugs for Urinary Frequency and Incontinence
  8. Drug

    Ramelteon

    go.drugbank.com/drugs/DB00980
    ApprovedInvestigational

    It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.

  9. Drug

    Ecamsule

    go.drugbank.com/drugs/DB09534
    Approved

    The company got approval for those products through a new drug application process. … It is a benzylidene camphor derivative, many of which are known for their excellent photostability.

    Mixtures: Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types, Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types
  10. Drug

    Uridine triacetate

    go.drugbank.com/drugs/DB09144
    Approved

    It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). … for incorporation into the genetic material of non-cancerous cells.