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Displaying results 771 - 780 of 10000 in total
  1. Drug

    Nitroxoline

    go.drugbank.com/drugs/DB01422
    Experimental

    It is a hydroxyquinoline derivative unrelated to other classes of drugs.[A179251] Nitroxoline is active against bacterial gyrases. … Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-NOK, 5-Nitrox
  2. Drug

    Androstenediol

    go.drugbank.com/drugs/DB01524
    ExperimentalIllicit

    Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by the oxidation of the 3-beta hydroxyl group … to a 3-keto group (3-hydroxysteroid dehydrogenases).

    Synonyms: 5-andendiol, 5-androstenediol
  3. Drug

    6-Hydroxy-5-undecyl-4,7-benzothiazoledione

    go.drugbank.com/drugs/DB04799
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole, 6-Hydroxy-5-undecyl-4,7-benzothiazoledione
  4. Drug

    Ritlecitinib

    go.drugbank.com/drugs/DB14924
    ApprovedInvestigational

    In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further approved by the EMA in September 2023. … [A260122,A260127] Other kinases have a cysteine at a position equivalent to Cys-909 in JAK3, and several of them belong to the TEC kinase family.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesSynonyms: 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)-
  5. Drug

    6-diazo-5-oxo-L-norleucine

    go.drugbank.com/drugs/DB17537
    Investigational

    6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist.

    Synonyms: 6-Diazo-5-oxo-L-norleucine
  6. Drug

    N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE

    go.drugbank.com/drugs/DB07997
    Experimental

    Synonyms: N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE
  7. Drug

    5-benzyl-1,3-thiazol-2-amine

    go.drugbank.com/drugs/DB08114
    Experimental

    Synonyms: 5-benzyl-1,3-thiazol-2-amine
  8. Drug

    CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE

    go.drugbank.com/drugs/DB08740
    Experimental

    Synonyms: CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE
  9. Drug

    9-(5,5-Difluoro-5-Phosphonopentyl)Guanine

    go.drugbank.com/drugs/DB04260
    Experimental

    Synonyms: 9-(5,5-Difluoro-5-Phosphonopentyl)Guanine
  10. Drug

    3,4-Dihydro-2'-deoxyuridine-5'-monophosphate

    go.drugbank.com/drugs/DB04280
    Experimental

    Synonyms: 3,4-Dihydro-2'-deoxyuridine-5'-monophosphate