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Displaying results 771 - 780 of 10000 in total
  1. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001732
    TargetHIV-2

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  2. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0004855
    TargetHuman immunodeficiency virus 1

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  3. Drug

    Alendronic acid

    go.drugbank.com/drugs/DB00630
    ApprovedInvestigational

    Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].

    Mixtures: OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET, ACIDO ALENDRONICO E COLECALCIFEROLO EGCategories: Drugs for Treatment of Bone Diseases
  4. Drug

    Dasatinib

    go.drugbank.com/drugs/DB01254
    ApprovedInvestigational

    Since dasatinib does not interact with some of the residues involved in those mutations, the use of this drug represents a therapeutic alternative for patients with cancers that have developed imatinib-resistance … [A11377,A33432] Dasatinib also inhibits a spectrum of kinases involved in cancer, including several SRC-family kinases.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
  5. Drug

    Buflomedil

    go.drugbank.com/drugs/DB13510
    Investigational

    Products: BUFLOMEDIL EG
  6. Drug

    Indobufen

    go.drugbank.com/drugs/DB12545
    Investigational

    Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.

    Products: INDOBUFENE EG
  7. Drug

    Levocetirizine

    go.drugbank.com/drugs/DB06282
    ApprovedInvestigational

    [L7694] Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine.[L7694] Levocetirizine was granted FDA approval in 1995.[L7694] … Levocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine].

    Mixtures: NORAVER ® GFAST CAPSULAS BLANDAS CONTRA LOS SINTOMAS DE LA GRIPA, BREATHEZY - LCategories: Antihistamines for Systemic Use
  8. Drug

    Ziprasidone

    go.drugbank.com/drugs/DB00246
    ApprovedInvestigational

    [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525] … [A190525] Luckily, several treatment options for psychotic disorders have been introduced to market since the realization of chlorpromazine's antipsychotic properties in 1952.

    Products: ZELDOX IM ENJ. SOL. ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADET, ZIPRASIDON AL 20MG HKP
  9. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. … It is also used in combination with [DB00366] (as the commercially available product Diclectin) for the treatment of nausea and vomiting in pregnancy.

    Mixtures: Pour Ma Santé, Vitamines Pour Bebes Et EnfantsCategories: Antiinfectives for Systemic Use, Drugs for Treatment of Tuberculosis
  10. Drug

    Ceftazidime

    go.drugbank.com/drugs/DB00438
    ApprovedInvestigational

    [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding

    Mixtures: CEFAZIME FOR INJECTION 1 g/vialCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use