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Displaying results 771 - 780 of 2454 in total
  1. Drug

    Umeclidinium

    go.drugbank.com/drugs/DB09076
    ApprovedInvestigational

    Umeclidinium is a long-acting muscarinic antagonist (LAMA) used as a maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD). COPD is a progressive obstructive lung disease characterized by shortness of breath,...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  2. Drug

    Pimobendan

    go.drugbank.com/drugs/DB11450
    ExperimentalVet approved

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  3. Drug

    Tildipirosin

    go.drugbank.com/drugs/DB11470
    ExperimentalVet approved

    Tildipirosin is a veterinary antibiotic.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  4. Drug

    Toluene

    go.drugbank.com/drugs/DB11558
    InvestigationalVet approved

    Toluene is a colorless, liquid that is immiscible in water. It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    Insulin argine

    go.drugbank.com/drugs/DB11564
    Experimental

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers
  6. Drug

    Insulin peglispro

    go.drugbank.com/drugs/DB11567
    Investigational

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers
  7. Drug

    Venetoclax

    go.drugbank.com/drugs/DB11581
    ApprovedInvestigational

    Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetocl...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  8. Drug

    Pirarubicin

    go.drugbank.com/drugs/DB11616
    Investigational

    Categories: P-glycoprotein substrates
  9. Drug

    Opicapone

    go.drugbank.com/drugs/DB11632
    ApprovedInvestigational

    Opicapone is a potent, reversible, and peripherally-acting third-generation inhibitor of catechol-o-methyltransferase (COMT), an enzyme involved in the breakdown of various catecholamines including dopamine. Many patients with Parkinson’...

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inhibitors
  10. Drug

    Amenamevir

    go.drugbank.com/drugs/DB11701
    Investigational

    Amenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers