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DB11616InvestigationalSmall molecule
Pirarubicin: Overview.
- Mechanism
- Curator reviewed
Pharmacologically active on DNA topoisomerase 2
- Formula / weight
- C32H37NO12 · 627.643 g/mol (avg)
- Also known as
- Theprubicin · THP-Adm · THP-Doxorubicin
Resolves to
Clinical / RWD
Structure
InChIKey
KMSKQZKKOZQFFG-YXRRJAAWSA-NSMILES[H][C@]1(N)C[C@]([H])(O[C@@]2([H])C[C@@](O)(CC3=C(O)C4=C(C(O)=C23)C(=O)C2=C(C=CC=C2OC)C4=O)C(=O)CO)O[C@@]([H])(C)[C@@]1([H])O[C@]1([H])CCCCO1Transporters
What you can answer from here — as of August 30, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
4TransportersSubstrate / inhibitor direction, not just membership
Listed above
Which companies are running trials of Pirarubicin, in which indications and phases, and which of those programs are still active?