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Displaying results 771 - 780 of 841 in total
  1. Drug

    Mineral oil

    go.drugbank.com/drugs/DB11057
    ApprovedInvestigationalVet approved

    Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. Petroleum mineral oil is manufactured from crude oils by vacuum distillation to produce several distillates and a residual oil that ar...

    Mixtures: Care One Hemorrhoidal
  2. Drug

    Lisocabtagene maraleucel

    go.drugbank.com/drugs/DB16582
    ApprovedInvestigational

    Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel. Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD1...

  3. Drug

    Tesmilifene

    go.drugbank.com/drugs/DB04905
    Investigational

    Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.

  4. Drug

    KP-1461

    go.drugbank.com/drugs/DB05644
    Investigational

    KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue. Designated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases.

  5. Drug

    Dabrafenib

    go.drugbank.com/drugs/DB08912
    ApprovedInvestigational

    Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic n...

  6. Drug

    Poliomyelitis virus type 3 (live, attenuated)

    go.drugbank.com/drugs/DB16579
    Investigational

    Mixtures: POLIO SABIN ONE AND THREE (ORAL) VACCINE
  7. Drug

    Anethole trithione

    go.drugbank.com/drugs/DB13853
    Approved

    Anethole trithione (ATT) appears to have a broad range of unique functions, from increasing salivary secretion to help treat xerostomia , to demonstrating an ability to inhibit carcinogenesis by increasing the activity of electrophile de...

  8. Drug

    Cloperastine

    go.drugbank.com/drugs/DB09002
    Investigational

    Cloperastine is a cough suppressant that acts on the central nervous system.

    Mixtures: Facol Classic One
  9. Drug

    Reslizumab

    go.drugbank.com/drugs/DB06602
    ApprovedInvestigational

    In addition, a significant improvement in lung function was seen, as measured by the volume of air exhaled by patients in one second [L1133].

  10. Drug

    Mepyramine

    go.drugbank.com/drugs/DB06691
    ApprovedVet approved

    Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination produc...

    Mixtures: Midol One