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Tozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigationalFDA on July 13, 2020. … [L15027] On December 11, 2020, the FDA issued an Emergency Use Authorization (EUA) based on 95% efficacy in clinical trials and a similar safety profile to other viral vaccines over a span of approximately
Mixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5Segesterone acetate
go.drugbank.com/drugs/DB14583ApprovedIt is commonly sold under the brand names Nestorone and Elcometrine and serves as an active component in hormonal contraceptives. … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 [A37048].
Papaya
go.drugbank.com/drugs/DB10658ApprovedPapaya allergenic extract is used in allergenic testing.
Mixtures: GNC Natural Brand Papaya Enzyme PlusLodoxamide
go.drugbank.com/drugs/DB06794ApprovedLodoxamide is marketed under the brand name Alomide by Alcon. … Lodoxamide is a mast-cell stabilizer for topical administration into the eye.
Tibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalIt has been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and the treatment of post-menopausal symptoms [L1720]. … Food and Drug Administration (FDA), advising the company that the New Drug Application (NDA) for tibolone had not been approved [L1722].
Products: TIBOLONE GENERIC PARTNERSNedosiran
go.drugbank.com/drugs/DB17635ApprovedInvestigational[A261685] Nedosiran was approved by the FDA on October 2<sup>nd</sup>, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 years of age and older and adults with primary
Dextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnDue to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. … The levo-isomer appears to exhibit a very limited antitussive effect.
Synonyms: d-PropoxypheneSofpironium
go.drugbank.com/drugs/DB19325Approved[L51103,L51108] It has also been available in Japan since 2020 under the brand name Ecclock.[L51103] … Sofpironium is a "soft" anticholinergic analog of [glycopyrronium] that has been modified with a readily hydrolyzable ester moiety.
Cytisine
go.drugbank.com/drugs/DB09028InvestigationalRecent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost. … Also known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treatment since 1964, and is relatively unknown in regions outside of central and Eastern Europe.
Quizartinib
go.drugbank.com/drugs/DB12874ApprovedInvestigational[A260641] Quizartinib was approved by the FDA in July 2023 and developed under the brand name VANFLYTA by Daiichi Sankyo. … cytarabine consolidation, followed by a maintenance monotherapy resulted in a 22% reduction in the risk of death.