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Displaying results 7831 - 7840 of 10000 in total
  1. Drug

    Trebananib

    go.drugbank.com/drugs/DB12056
    Investigational

    Trebananib is under investigation for the treatment of Ovarian Cancer, Peritoneal Cancer, and Fallopian Tube Cancer. … Trebananib has been investigated for the treatment of Cancer, Oncology, Carcinoma, Metastases, and Colon Cancer, among others.

  2. Drug

    Uridine diphosphate glucose

    go.drugbank.com/drugs/DB01861
    Experimental

    Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. … Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5'-Diphosphoglucose, Uridine-5'-Diphosphoglucose
  3. Drug

    Thalagen

    go.drugbank.com/drugs/DB17714
    Experimental

    It is being investigated for the treatment of beta-thalassemia.[L46168] … It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral vector encoding the normal human beta-globin gene.

  4. Drug

    AVR-RD-05

    go.drugbank.com/drugs/DB18631
    Experimental

    AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. … It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).

    Synonyms: Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase (IDS) enzyme to subjects with Hunter syndrome
  5. Drug

    Giredestrant

    go.drugbank.com/drugs/DB19125
    Investigational

    Giredestrant is under investigation in clinical trial NCT06065748 (A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With Er-positive … , Her2-negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (Pionera Breast Cancer)).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)-3-azetidinyl)amino)phenyl)-.beta.,.beta.-difluoro-1,3,4,9-tetrahydro-3-methyl-2h-pyrido(3,4-b)indole-2-propanol, 3-((1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2h-pyrido(3,4-b)indol-2-yl)-2,2-difluoropropan-1-ol
  6. Drug

    Trestolone

    go.drugbank.com/drugs/DB05830
    Investigational

    Trestolone (7α-methyl-19-nortestosterone) is a synthetic androgen developed by the Population Council as a potential candidate drug for use in hormonal male contraceptive methods. … In males, regular administration of sufficient quantities of trestolone induces a state of temporary infertility.

    Synonyms: 17beta-Hydroxy-7alpha-methylestr-4-en-3-one, 7alpha-Methyl-3-oxo-4-estren-17beta-ol
  7. Drug

    N-Ethylretinamide

    go.drugbank.com/drugs/DB03917
    Experimental

    N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.

    Categories: Vitamin ASynonyms: all-trans-N-Ethylretinamide, Vitamin A acid ethylamide
  8. Drug

    BMS-690514

    go.drugbank.com/drugs/DB11665
    Investigational

    BMS-690514 has been investigated for the treatment of Breast Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Carnosine

    go.drugbank.com/drugs/DB11695
    Investigational

    Carnosine has been investigated for the treatment of Gulf War Illness.

    Synonyms: L-Carnosine
  10. Drug

    Danusertib

    go.drugbank.com/drugs/DB11778
    Investigational

    Danusertib has been used in trials studying the treatment of Leukemia.

    Categories: Heterocyclic Compounds, 1-Ring