Search

Displaying results 7841 - 7850 of 10000 in total
  1. Target

    Dipeptidyl peptidase 1

    go.drugbank.com/bio_entities/BE0013736
    TargetHumans

    Thiol protease (PubMed:1586157). Has dipeptidylpeptidase activity (PubMed:1586157). Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids (PubMed:1586157). Proline cannot occupy the P1 po...

    Polypeptides: Dipeptidyl peptidase 1
  2. Target

    Lysocardiolipin acyltransferase 1

    go.drugbank.com/bio_entities/BE0015711
    EnzymeHumans

    Also exhibits 1-acyl-sn-glycerol-3-phosphate acyltransferase activity (AGPAT) activity; converts 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3- phosphate

    Polypeptides: Lysocardiolipin acyltransferase 1Synonyms: 1-AGPAT 8, 1-AGP acyltransferase 8
  3. Target

    Pyroglutamyl-peptidase 1

    go.drugbank.com/bio_entities/BE0020171
    TargetHumans

    Removes 5-oxoproline from various penultimate amino acid residues except L-proline

    Polypeptides: Pyroglutamyl-peptidase 1Synonyms: 5-oxoprolyl-peptidase
  4. Drug

    Retapamulin

    go.drugbank.com/drugs/DB01256
    Approved

    Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ALTARGO UNGUENTO 1%
  5. Pathway

    De Novo Triacylglycerol Biosynthesis TG(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0021133
    Metabolic

    Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic … The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: Diacylglycerol O-acyltransferase 1, 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha
  6. Pathway

    De Novo Triacylglycerol Biosynthesis TG(14:1(9Z)/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0021153
    Metabolic

    Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic … The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: Diacylglycerol O-acyltransferase 1, 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha
  7. Pathway

    De Novo Triacylglycerol Biosynthesis TG(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0021544
    Metabolic

    Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic … The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: Diacylglycerol O-acyltransferase 1, 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha
  8. Pathway

    De Novo Triacylglycerol Biosynthesis TG(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0021549
    Metabolic

    Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic … The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: Diacylglycerol O-acyltransferase 1, 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha
  9. Pathway

    De Novo Triacylglycerol Biosynthesis TG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0021620
    Metabolic

    Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic … The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: Diacylglycerol O-acyltransferase 1, 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha
  10. Pathway

    De Novo Triacylglycerol Biosynthesis TG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0021625
    Metabolic

    Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic … The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: Diacylglycerol O-acyltransferase 1, 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha