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Displaying results 7851 - 7860 of 10000 in total
  1. Drug

    Denifanstat

    go.drugbank.com/drugs/DB17576
    Investigational

    Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.

  2. Drug

    AVI-5126

    go.drugbank.com/drugs/DB05726
    Investigational

    AVI-526 is an improved formulation of [AVI-4557], developed for use on Vein Grafts before use in Heart by-Pass Graft Surgery. … The drug was under investigation in clinical trial NCT00451256 (Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG)).

  3. Drug

    Ergosterol

    go.drugbank.com/drugs/DB04038
    ApprovedWithdrawn

    A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result … in ERGOCALCIFEROL.

    Synonyms: (22E,24S)-24-methylcholesta-5,7,22-trien-3β-ol, Provitamin D2
  4. Drug

    GSK-923295

    go.drugbank.com/drugs/DB06097
    Investigational

    GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of colon, breast, ovarian, lung and other tumors. … GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline

  5. Drug

    NGD-4715

    go.drugbank.com/drugs/DB06027
    Experimental

    NGD-4715 is an investigational compound developed for the treatment of Obesity. NGD-4715 functions as a melanin-concentrating hormone receptor 1 antagonist.

  6. Drug

    Tromantadine

    go.drugbank.com/drugs/DB13288
    Approved

    Tromantadine is marketed as Viru-Merz in the Czech Republic [L5740]. It is an antiviral used in the treatment of herpes zoster and simplex.

  7. Drug

    Rivanicline

    go.drugbank.com/drugs/DB05855
    Experimental

    It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. … Rivanicline also has stimulant and analgesic actions which are thought due to increased noradrenaline release.

    Synonyms: (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine, (E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine
  8. Drug

    Hyaluronic acid (non-animal stabilized)

    go.drugbank.com/drugs/DB19175
    ApprovedWithdrawn

    Hyaluronic acid (non-animal stabilized) is under investigation in clinical trial NCT03460158 (Prospective Evaluation of Facial Cosmetic Procedures).

    Synonyms: Hyaluronan (non animal), Hyaluronic acid (non-animal stabilized)
  9. Drug

    Afimoxifene

    go.drugbank.com/drugs/DB04468
    Investigational

    This technology enables percutaneous delivery of drugs that cannot be delivered orally. It is being developed by Ascent Therapeutics. … Afimoxifene (4-Hydroxytamoxifen, trade name TamoGel) is a new estrogen inhibitor under investigation for a variety of estrogen-dependent conditions, including cyclic breast pain and gynecomastia.

  10. Drug

    Josamycin

    go.drugbank.com/drugs/DB01321
    Investigational

    The drug has antimicrobial activity against a wide spectrum of pathogens.