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Darifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalDarifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Categories: Genito Urinary System and Sex Hormones, Cytochrome P-450 SubstratesSynonyms: (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamideTezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigationalAsthma is a heterogeneous chronic obstructive respiratory disease with both "type 2" (T2) and T2-low endotypes characterized by reduced airflow, chronic inflammation, and airway remodelling. … [A243764, A243769] Thymic stromal lymphopoietin (TSLP), an innate pleiotropic IL-2-family cytokine, has emerged as a key upstream regulator of chronic inflammation across asthma endotypes.
Synonyms: AMG 157, AMG-157Products: Tezspire 210 mg/1,91 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), TEZSPIRE®Factor IX Complex (Human)
go.drugbank.com/drugs/DB11330ApprovedInvestigationalwith Hemophilia B (Factor IX deficiency). … Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma.
Categories: Factor IXSynonyms: Coagulation factor IX, II, VII and X in combination, Factor IX ComplexInsulin human
go.drugbank.com/drugs/DB00030ApprovedInvestigationalAfrezza does not currently have Health Canada or European Medicines Agency approval for marketing in Canada or the EU. … Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: INSUMAN COMB 25 100I E/ML, INSUMAN COMB 25 100I E/MLCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersDimethicone
go.drugbank.com/drugs/DB11074ApprovedInvestigationalA study found that that the 100 % dimethicone product is a safe and highly effective head lice treatment for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing … Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties.
Salts: Dimethicone 100Mixtures: PANKREOFLAT 170/310 MG GRANÜL (22x2 g poşet), Cellisys EX Wrinkle SolutionLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigational[A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.
Mixtures: Dg Health Anti Diarrheal Anti GasCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. … [A175042,A191529] Neomycin A, or [neamine], is a moiety that conjoins two molecules of neomycin B and C together.
Mixtures: THIOCILLINE 500 IU/G + 5 MG/G DERİ MERHEMİ, 30 G, THIOCILLINE 500 IU/G + 5 MG/G GÖZ MERHEMİ, 5 GRCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexChloroprocaine
go.drugbank.com/drugs/DB01161ApprovedInvestigational[L43402] The pharmacological profile of chloroprocaine is characterized by a short latency and duration, similar to the one observed with [lidocaine]. … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without methylparaben as a preservative.
Synonyms: 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate, 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl esterProducts: Ampres 20 mg/ml Injektionslösung, Nesacaine Ce 2% Inj 20mg/mlCyproterone acetate
go.drugbank.com/drugs/DB04839ApprovedInvestigationalIt is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Mixtures: ESTELLE-35 ED TABLET, FACETIX MINI 20 TABLETA RECUBIERTACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsTiaprofenic acid
go.drugbank.com/drugs/DB01600ApprovedTiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain.
Categories: Non COX-2 selective NSAIDSSynonyms: 2-(5-Benzoyl-thiophen-2-yl)-propionic acid, 2-(5-Benzyl-2-thienyl)propionsäure