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Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs. … [L13290,L13296] A subcutaneous formulation of daratumumab co-formulated with hyaluronidase-fihj is also approved for the treatment of adults with multiple myeloma.
Products: DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 400MG/20ML, DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5MLLanolin
go.drugbank.com/drugs/DB11112ApprovedLanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. … Lanolin primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides. For this reason, it is also called wool wax or wool grease.
Mixtures: Kendra SKIN PROTECTION and PAIN RELIEF FOR HAIR REMOVAL, Skullduggery Pain Relief and Skin Protection for TattoosCategories: Compounds used in a research, industrial, or household settingPiperonyl butoxide
go.drugbank.com/drugs/DB09350ApprovedVet approvedPiperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. … Piperonyl butoxide is a semisynthetic derivative of safrole.
Mixtures: Mata Piojos A Pediculicide Low Foaming, Para Special Shampoo for Lice & NitsCategories: Compounds used in a research, industrial, or household settingStrontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnStrontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. … Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an
Categories: Drugs for Treatment of Bone DiseasesProducts: PROTOS Granules for Oral Suspension 2gXylometazoline
go.drugbank.com/drugs/DB06694Approved[A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies. … In some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol].
Mixtures: Ophtrivin A Ophthalmic Dps, nasic pur NasensprayProducts: XYLOMETAZOLIN0.1%NAS STA L, NASENGEL ALBetrixaban
go.drugbank.com/drugs/DB12364ApprovedBetrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks … for VTE [A27285].
Categories: Factor Xa Inhibitors, Direct factor Xa inhibitorsCoagulation factor X human
go.drugbank.com/drugs/DB13148ApprovedInvestigationalIt is a two-chain glycoprotein with the molecular weight of approximately 59 kDa [A31472]. … However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe hereditary Factor X deficiency.
Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTIONIbalizumab
go.drugbank.com/drugs/DB12698ApprovedInvestigationalIn October 2022, the FDA approved the administration of Trogarzo (ibalizumab-uiyk) by intravenous push, allowing for a faster drug administration.[L43443,L43448] … This drug was approved in March 2018 for the management of treatment-resistant HIV [L1554].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTrandolapril
go.drugbank.com/drugs/DB00519ApprovedInvestigationalATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.
Categories: Antihypertensive Agents Indicated for HypertensionLefamulin
go.drugbank.com/drugs/DB12825ApprovedLefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia. … [A183161] The chemical structure of lefamulin contains a tricyclic mutilin core that is necessary for some of its antimicrobial activity.[A183167]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use