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Tralesinidase alfa
go.drugbank.com/drugs/DB17657InvestigationalIt is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.[A258828] … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2.
Categories: beta-N-AcetylhexosaminidasesSynonyms: Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein, Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2NSI-566
go.drugbank.com/drugs/DB17954InvestigationalDeveloped by Seneca Biopharma, it is being investigated for the treatment of amyotrophic lateral sclerosis (ALS), stroke, and chronic spinal cord injury (cSCI).[L47097] … NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells.
Macozinone
go.drugbank.com/drugs/DB14821InvestigationalMacozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169).
Categories: Drugs for Treatment of TuberculosisSt. John's Wort
go.drugbank.com/drugs/DB01323ApprovedNutraceuticalMixtures: R. FormulaCategories: Antidepressive Agents Indicated for Depression, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeThalagen
go.drugbank.com/drugs/DB17714ExperimentalIt is being investigated for the treatment of beta-thalassemia.[L46168] … Thalagen is a branded product developed by San Rocco Therapeutics.
FP0011
go.drugbank.com/drugs/DB05090ExperimentalIt acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties. … FP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease).
Tifuvirtide
go.drugbank.com/drugs/DB05413InvestigationalTifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
KOS-1584
go.drugbank.com/drugs/DB05903InvestigationalKOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. … KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
Vatiquinone
go.drugbank.com/drugs/DB11917InvestigationalVatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type.
Dociparstat sodium
go.drugbank.com/drugs/DB16481InvestigationalSynonyms: 2,3-o-Desulfated heparin (12000 da)Categories: Experimental Unapproved Treatments for COVID-19