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Displaying results 7931 - 7940 of 10000 in total
  1. Drug

    Proscillaridin

    go.drugbank.com/drugs/DB13307
    Experimental

    Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). … Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations [A27193

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Ruserontinib

    go.drugbank.com/drugs/DB21555
    Investigational

    Ruserontinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Ruserontinib is a tyrosine kinase inhibitor. … Ruserontinib is under investigation in clinical trial NCT04716114 (A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated).

    Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Vociprotafib

    go.drugbank.com/drugs/DB21559
    Investigational

    Vociprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Vociprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor. … Vociprotafib has a monoisotopic molecular weight of 450.16 Da.

  4. Drug

    Enbezotinib

    go.drugbank.com/drugs/DB21565
    Investigational

    Enbezotinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Enbezotinib is a tyrosine kinase inhibitor. … Enbezotinib has a monoisotopic molecular weight of 424.17 Da.

  5. Drug

    Amelubant

    go.drugbank.com/drugs/DB06248
    Investigational

    Synonyms: Carbamic acid, N-[[4-[[3-[[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]methyl]phenyl]methoxy]phenyl]iminomethyl]-, ethyl ester
  6. Drug

    Gavestinel

    go.drugbank.com/drugs/DB06741
    Experimental

    Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM). … Gavestinel displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites and is orally bioavailable and active in vivo.

    Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Lersivirine

    go.drugbank.com/drugs/DB11649
    Investigational

    Lersivirine has been used in trials studying the treatment of HIV-1.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    BMS-903452

    go.drugbank.com/drugs/DB11773
    Investigational

    BMS-903452 has been used in trials studying the treatment of Diabetes.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Hyodeoxycholic Acid

    go.drugbank.com/drugs/DB11789
    Investigational

    Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.

  10. Drug

    Lampalizumab

    go.drugbank.com/drugs/DB11826
    Investigational

    Lampalizumab has been used in trials studying the treatment of Geographic Atrophy.