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Solifenacin
go.drugbank.com/drugs/DB01591ApprovedInvestigationalSolifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. … [L7511] Solifenacin was granted FDA approval on 19 November 2004.[L7511]
Categories: tamsulosin and solifenacin, Genito Urinary System and Sex HormonesProducts: VESIKUR 10MG, VESICARE 10MGAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalDeveloped by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with … Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
Categories: Diazepines, Oxazepines, Thiazepines and Oxepines, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: SAPHRIS SUBLINGUAL TABLET 10MG, SYCREST 10MG DILALTI TABLET, 100 TABLETApixaban
go.drugbank.com/drugs/DB06605ApprovedInvestigationalApixaban was approved by the FDA on December 28, 2012[L6043]. … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic
Categories: Blood and Blood Forming OrgansProducts: Nb-apixaban, Nb-apixaban TabletErythromycin
go.drugbank.com/drugs/DB00199ApprovedInvestigationalVet approvedErythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists … [L5245] Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and gram-negative bacteria.
Mixtures: Erythromycin and Benzoyl Peroxide, Erythromycin and Benzoyl PeroxideCategories: Erythromycin and similars, Macrolides, Lincosamides and StreptograminsFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Categories: Fluorouracil and prodrugs, Skin and Mucous Membrane AgentsProducts: BENDA 5 FU 50MG/ML 250MG, 5-FU INJECTION 250MG/5ML FLAKON, 10 ADETKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigational[A231204] Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. … available and indicated as an add-on therapy for children with atopic asthma.
Categories: Decongestants and AntiallergicsProducts: Up and Up Eye Itch Relief, Nu-ketotifen Syrup - 1mg/5mlRilpivirine
go.drugbank.com/drugs/DB08864ApprovedInvestigational[A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. … [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's
Mixtures: Emtricitabine, Rilpivirine and Tenofovir Disoproxil Fumarate, Odefsey® (200mg Emtricitabine/25mg Rilpivirine/25mg Tenofovir alafenamide) film coated tabletsCategories: dolutegravir and rilpivirine, emtricitabine, tenofovir disoproxil and rilpivirineChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule cells in the kidney. … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment.
Mixtures: ATENOCOMP 1A 100MG/25MG, ATENOCOMP 1A 100MG/25MGCategories: chlortalidone and potassium, chlortalidone and potassium-sparing agentsAntihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalPEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529]. … Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product _Adynovate_ [FDA label].
Categories: Amino Acids, Peptides, and ProteinsProducts: ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONTiclopidine
go.drugbank.com/drugs/DB00208ApprovedThe FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke.
Categories: Blood and Blood Forming Organs, Metabolic Side Effects of Drugs and SubstancesProducts: Ticlid Tab 250mg, TIODIN TABLET 250MG