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Resmetirom
go.drugbank.com/drugs/DB12914ApprovedInvestigationalOn March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD … [L50336] Thyroid hormones directly regulate lipid metabolism in the liver; thus, impaired thyroid function, such as low serum thyroid hormone levels, is often observed in NAFLD.
Imlifidase
go.drugbank.com/drugs/DB15258ApprovedInvestigational[A225916] Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life. … [A225836] As a result, highly sensitized individuals experience marked delays on transplant lists due to the challenges associated with procuring an HLA compatible donor graft.
Arginine
go.drugbank.com/drugs/DB00125ApprovedInvestigationalNutraceuticalAn essential amino acid that is physiologically active in the L-form.
Mixtures: Conopeptide Deer Bone Collagen Nano Instant Essence Filling Set, TRAVASOL SOLUCION 8.5% CON ELECTROLITOSProducts: Non-proprietary nameRituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalOn November 28, 2018, the US FDA approved _Truxima_, the first biosimilar to Rituxan (Rituximab) [L4808]. … Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes.
Hyaluronic acid
go.drugbank.com/drugs/DB08818ApprovedInvestigationalVet approved[A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in oral, topical, and injectable forms. … Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934.
Mixtures: Conopeptide Deer Bone Collagen Nano Instant Essence Filling Set, Kaewoon for MenCategories: Compounds used in a research, industrial, or household settingEtoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalAccumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. … This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding.
Products: INJECTION ETOPOSIDE CS 100MG IN 5ML, SINTOPOZID 100 MG/5 ML IV KON. INFUZYON COZELTISI ICEREN FLAKON, 1 ADETAluminum chloride
go.drugbank.com/drugs/DB11081ApprovedInvestigationalIn antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15%, calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012]. … It may also be found in over-the-counter as an antiperspirant or prescription products as an antihemorrhagic agent.
Mixtures: Anti-perspirant Roll-ON Deod, Youth Dew Roll On Antipersp Deod LotCategories: Compounds used in a research, industrial, or household settingEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approvedvarious tissues including in the breasts, uterus, ovaries, skin, prostate, bone, fat, and brain. … Estradiol valerate is also available in combination with [DB09123] as the commercially available product Natazia used for the prevention of pregnancy and for the treatment of heavy menstrual bleeding.
Mixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15Ensartinib
go.drugbank.com/drugs/DB14860ApprovedInvestigational[A273963, A273958] Ensartinib is a first-line treatment for anaplastic lymphoma kinase (ALK)-mutated non-small cell lung cancer (NSCLC). … received an ALK-inhibitor on December 18, 2024.
Estradiol benzoate
go.drugbank.com/drugs/DB13953ApprovedVet approvedWithdrawnEstradiol benzoate is not currently available in Canada or the US. … in various tissues including in the breasts, uterus, ovaries, skin, prostate, bone, fat, and brain.