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Varenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalA full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, Chantix, has been associated with seizures and that some patients who drink while taking the drug may
Mixtures: CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET, CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADETProducts: CHAMPIX 1 MG 56 FILM KAPLI TABLET, CHAMPIX 1.0 MG TABLETAS RECUBIERTASInsulin detemir
go.drugbank.com/drugs/DB01307ApprovedInvestigational[A2358, A2359, A2360, A44] As a result, people with T1D rely primarily on exogenous forms of insulin, such as insulin detemir, to lower glucose levels in the blood. … [A2358, A2359, A2360, A44] Marketed as the brand name product Levemir, insulin detemir has a duration of action of 16-24 hours allowing for once-daily dosing, typically at bedtime.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: LEVEMIR PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 5 ADET, LEVEMIR FLEXPEN 100U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADETObinutuzumab
go.drugbank.com/drugs/DB08935ApprovedInvestigational[L54521] It was developed as a Type II anti-CD20 antibody to improve upon first-generation agents like rituximab. … [A274631] Structurally, obinutuzumab is glycoengineered, meaning the fucose content of its Fc region has been reduced.
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION, GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 MLQuinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigational[A184844] Quinapril was granted FDA approval on 19 November 1991.[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423] … [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Mixtures: ACCUZIDE 20 MG/12.5 MG FILM TABLET, 30 ADET, ACCUZIDE FORT 20 MG/25 MG FILM KAPLI TABLET, 30 ADETProducts: ACCUPRIL (TABLETS 10 MG ), QUINAPRIL 10 MG TABLETASFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalIt is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazineSotalol
go.drugbank.com/drugs/DB00489ApprovedInvestigational[A178579] It was the first of the class III anti arrhythmic drugs.[A178579] Sotalol was first approved as an oral tablet on 30 October 1992. … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: TALOZIN 40 MG/4 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, SOTALEX 160 MGRitodrine
go.drugbank.com/drugs/DB00867ApprovedWithdrawnAdrenergic beta-agonist used to control premature labor.
Products: PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPULGlycolic acid
go.drugbank.com/drugs/DB03085ApprovedMixtures: GLYCOLIC Acid 50 BUFFERED Skin Chemical Peel, GLYCOLIC Acid 70 BUFFERED Skin Chemical PeelProducts: GLYCOLIC Acid 50 Skin Chemical Peel, bdr Re-action deep low base skin refiner exfoliation essenceInsulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigational[A18561,A18562,A18563,A18564,A174934] Compared to available long-acting analogs such as [DB00047] and [DB01307], which have a duration of action of 20-24 hours, insulin degludec provides a consistent level … [A18561,A18562,A18563,A18564,A174934] As a result, people with T1D rely primarily on exogenous forms of insulin, such as insulin degludec, to lower glucose levels in the blood.
Mixtures: RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 10 ADET, RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 5 ADETCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigational[A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings … C1-Like 1 (NPC1L1), and is unique in that it does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids.
Mixtures: Rosamib 5 mg/10 mg Tabletten, Ezerosu 10 mg/5 mg-FilmtablettenCategories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP3A Inhibitors