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Troriluzole
go.drugbank.com/drugs/DB15079InvestigationalTroriluzole is under investigation in clinical trial NCT03701399 (Troriluzole in Adult Subjects With Spinocerebellar Ataxia).
Pimicotinib
go.drugbank.com/drugs/DB18972InvestigationalIt was initially developed by Abbisko Therapeutics Co in collaboration with Merck KGaA. [L53748] Pimicotinib was granted Fast Track Designation in December 2023 by the FDA. [L53753] … Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)).
Synonyms: 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-, 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamideSW033291
go.drugbank.com/drugs/DB32765Experimental[A275473, A275474] It has been found to increase prostaglandin E2 (PGE2) and is being investigated in accelerating of hematopoietic recovery and treating type 2 diabetes mellitus.[A275473, A275474] … SW033291 is a small molecule 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor.
Galocitabine
go.drugbank.com/drugs/DB21373ExperimentalThe usage of the INN stem '-citabine' in the name indicates that Galocitabine is a nucleoside antiviral or antineoplastic agent, cytarabine or azacitidine derivative. … Galocitabine is a small molecule drug.
Ancitabine
go.drugbank.com/drugs/DB20595ExperimentalThe usage of the INN stem '-citabine' in the name indicates that Ancitabine is a nucleoside antiviral or antineoplastic agent, cytarabine or azacitidine derivative. … Ancitabine is a small molecule drug.
Evifacotrep
go.drugbank.com/drugs/DB21510InvestigationalEvifacotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Evifacotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.
Carafiban
go.drugbank.com/drugs/DB19813ExperimentalCarafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Carafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Licostinel
go.drugbank.com/drugs/DB19864ExperimentalLicostinel is a small molecule drug. The usage of the INN stem '-stinel' in the name indicates that Licostinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist.
Roxifiban
go.drugbank.com/drugs/DB21089ExperimentalRoxifiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Roxifiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Sibrafiban
go.drugbank.com/drugs/DB21420ExperimentalSibrafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Sibrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).