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Orbofiban
go.drugbank.com/drugs/DB20676ExperimentalOrbofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Orbofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Gantofiban
go.drugbank.com/drugs/DB20951ExperimentalGantofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Gantofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Zerencotrep
go.drugbank.com/drugs/DB21710ExperimentalZerencotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Zerencotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.
TMC-310911
go.drugbank.com/drugs/DB15623Investigational[L12045] It is being investigated for use in HIV-1 infections. … [L12045,A191643] TMC-310911 is currently being investigated, in combination with other HIV therapies and antivirals, as a potential treatment for COVID-19 caused by SARS-CoV-2.[L12012]
Petesicatib
go.drugbank.com/drugs/DB15297InvestigationalPetesicatib is under investigation in clinical trial NCT02295332 (A Study of RG7625 in Healthy Volunteers).
Masilukast
go.drugbank.com/drugs/DB16227InvestigationalMasilukast is under investigation in clinical trial NCT01740986 (Safety and Efficacy of SA09012 in Asthma).
Thienylfentanyl
go.drugbank.com/drugs/DB09180ExperimentalIllicitThienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the Federal Analog Act scheduled drugs based on structural similarity rather than scheduling drugs individually … Thienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide.
Bizalimogene ralaplasmid
go.drugbank.com/drugs/DB16113InvestigationalBizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related … Anal or Anal/peri-anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2).
Bicuculline
go.drugbank.com/drugs/DB11562ExperimentalIt was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors.
Londamocitinib
go.drugbank.com/drugs/DB19190InvestigationalLondamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high
Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-