Search
De Novo Triacylglycerol Biosynthesis TG(i-24:0/22:0/16:0)
smpdb.ca/view/SMP0042774MetabolicTriglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. … (Wikipedia) De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue.
De Novo Triacylglycerol Biosynthesis TG(i-24:0/8:0/20:0)
smpdb.ca/view/SMP0042807MetabolicTriglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. … (Wikipedia) De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue.
Simeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnAccording to 2017 American Association for the Study of Liver Diseases (AASLD) and 2015 consensus guidelines from the Canadian Association for the Study of the Liver (CASL), simeprevir can be used as first-line … Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsFlortaucipir F-18
go.drugbank.com/drugs/DB14914ApprovedInvestigational[A203933, A203936, A203939] Although flortaucipir F-18 displays low levels of background binding throughout the brain,[A203936] it does display off-target binding to monoamine oxidase MAO-A and MAO-B … It was approved by the FDA on May 28, 2020, for sale by Avid Radiopharmaceuticals under the name TAUVID™ and is the first FDA-approved molecule for imaging aggregated tau protein in the brain.[L14114]
Synonyms: Flortaucipir F 18Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingInolimomab
go.drugbank.com/drugs/DB15628InvestigationalIt has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385] … Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease.
Synonyms: Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain), disulfide with mouse monoclonal B-B10 kappa-chain, dimerCategories: Receptors, Interleukin-2Diltiazem Calcium Channel Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126292Drug action, and rest-related cramps in the lower extremities. … Some side effects of using diltiazem may include dizziness, flushing, headache, and weakness.
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferaseL-aminocarnityl-succinyl-leucyl-argininal-diethylacetal
go.drugbank.com/drugs/DB06124ExperimentalC-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal … C-101 includes a carnitine carrier molecule and a leupeptin analogue, a known calpain inhibitor. Calpain is the primary protease that degrades skeletal muscle.
Alanine
go.drugbank.com/drugs/DB00160ApprovedInvestigationalNutraceuticalAlanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination.
Synonyms: L-α-alanine, (S)-2-aminopropanoic acidMixtures: 4.25%travasol Amino Acid InJ.W.elecw.5%dex., 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.Carbamoylcholine
go.drugbank.com/drugs/DB00411ApprovedCarbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. … [A226315] Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and other parasympathetic effects.
Categories: Compounds used in a research, industrial, or household settingProducts: Isopto Carbachol 3%, MIOSTAT %0.01 İNTRAOKÜLER ÇÖZELTİ (1 ADET)Eftrenonacog alfa
go.drugbank.com/drugs/DB11608ApprovedHemophilia B is a blood disorder with an incidence of approximately once every 30,000 male births in all populations and ethnic groups [A31557]. … It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016.
Products: ALPROLIX® 250 UI