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Synthetic Conjugated Estrogens, B
go.drugbank.com/drugs/DB09318ApprovedSynthetic conjugated estrogens, B tablets contain a blend of ten synthetic estrogenic substances. … This blend of ten estrogen derivatives are plant-derived forms of endogenous estrogens and contain many of the same compounds as the Conjugated Equine Estrogens (CEEs), although they are not considered
Ferrous aspartate
go.drugbank.com/drugs/DB13220ExperimentalThe use of ferrous acetate over ferrous sulfate is currently undergoing an investigation by a clinical trial [L5464]. It is also used for dying of fabric or leather and as a wood preservative.
Mixtures: Ultimate OB DHAPoloxamer 188
go.drugbank.com/drugs/DB11333ApprovedDue to its sufactant properties, P188 may also be found in over-the-counter (OTC) products such as toothpaste, laxatives and mouthwash, and used in various cosmetic, industrial and pharmaceutical applications … The ability of P188 in attenuating membrane damage and cell injury has been demonstrated in a variety of _in vivo_ and _in vitro_ models [A27218].
Categories: Compounds used in a research, industrial, or household settingAvacincaptad pegol
go.drugbank.com/drugs/DB15165ApprovedInvestigational[L47696] AMD is the leading cause of vision loss in developed countries for people over 50 years old, with a global estimate of 170 million individuals affected. … AMD eventually progresses to bilateral and irreversible loss of vision, whether or not the patients have the non-neovascular (dry) or the neovascular (wet) form of AMD.
Diacylglycerol lipase alpha
go.drugbank.com/bio_entities/BE0009155TargetHumansSynonyms: Sn1-specific diacylglycerol lipase alphaKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigational[L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Products: Nu-ketorolac, Nu-ketorolac Ophthalmic SolutionAvacopan
go.drugbank.com/drugs/DB15011ApprovedInvestigational[A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified a key role for the alternative complement pathway and, in particular, the interaction between the anaphylatoxin … by the presence of ANCAs in the serum.
Blinatumomab
go.drugbank.com/drugs/DB09052ApprovedInvestigational[L46991,L46996] Blinatumomab has a short half-life, requiring patients to receive a continuous infusion over 4-week cycles using a portable mini-pump for optimum delivery.[A254826] … [A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of malignant B-cells.
Alteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalHowever, its use for the treatment of acute ischemic stroke (AIS) has increased over the years. … In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.
Products: ACTILYSE 20 MG FLAKON, 1 ADET, ACTILYSE 10 MG FLAKON, 1 ADETTriamterene
go.drugbank.com/drugs/DB00384Approved[L6166] It is also found in a combination product with hydrochlorothiazide that is used for the management of hypertension or treatment of edema in patients who develop hypokalemia on hydrochlorothiazide … It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side.
Mixtures: Nu-triazide Tab 50 Mg/25 mg, TRIANSERIL 50 MG/25 MG KAPSUL, 250 ADET