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Tiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigational[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than [ipratropium]. … [A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.
Categories: Drugs for Obstructive Airway Diseases, Agents to Treat Airway DiseaseProducts: SPIRIVA® RESPIMAT® RE-USABLE SOLUTION FOR INHALATION 2.5 MICROGRAM, Spiriva Respimat, 2.5 microgram, Solution for InhalationEfmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalFactor VIII is a blood coagulant factor involved in the intrinsic pathway to form fibrin, or a blood clot. … It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It is suitable for all age groups.
Products: ELOCTATE® 250 UI, ELOCTATE® 500 UIAminocaproic acid
go.drugbank.com/drugs/DB00513ApprovedInvestigationalAn antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Mixtures: Gray Salt, Salt ToothInternational brands: Kai Nai YinIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalResistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label]. … Following administration, isavuconazonium undergoes biotransformation to form the active moiety, isavuconazole, for the antifungal actions.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: CRESEMBA (POWDER FOR SOLUTION FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200 MG/VIAL)Streptomycin
go.drugbank.com/drugs/DB01082ApprovedInvestigationalVet approved[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity. … Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSynonyms: 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranosideIsavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigational[A6913,A6914,A262706] On December 08, 2023, the FDA approved the expanded use of isovuconazonium in pediatric patients for the same indications.[L49251] … Due to low solubility in water of isavuconazole on its own, the isovuconazonium formulation is favorable as it has high solubility in water and allows for intravenous administration.
Products: CRESEMBA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200MGCarboxymethylcellulose
go.drugbank.com/drugs/DB11059ApprovedInvestigationalIt is added in food products as a viscosity modifier or thickener and emulsifier. … The viscous and mucoadhesive properties as well as its anionic charge allow prolonged retention time in the ocular surface [A33029]. Sodium carboxymethylcellulose is the most commonly used salt.
Mixtures: Clear Eyes for Dry Eyes, GenTeal Moderate to SevereCategories: Compounds used in a research, industrial, or household settingEpendymoma
go.drugbank.com/conditions/DBCOND0017183Drugs: CarmustineSynonyms: Ependymoma, no International Classification of Diseases for Oncology subtype, Ependymoma, no ICD-O subtypeCamphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnIt appears in the list of drug products withdrawn or removed from the market for safety or effectiveness. … The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%.
Mixtures: Thunas Salve for Rheumatic Pains, CHAP ICE (R) MEDICATEDSynonyms: Camphor D-form, (R)-camphorPralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigationalPralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. … [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes.
Synonyms: N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid, (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acidProducts: SOLUTION FOR INFUSION 20MG/ML, Folotyn 20mg/ml Solution for Infusion