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Displaying results 801 - 810 of 10000 in total
  1. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery. … Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase

    Salts: Sennosides A and BMixtures: Laxatif De Sene Et Docusate De Sodium, Senna-S
  2. Drug

    Alnus glutinosa

    go.drugbank.com/drugs/DB15904
    Experimental

    Synonyms: European alder bark, European black alder bark
  3. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A188826,A188832] Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal

    Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  4. Drug

    Ambrisentan

    go.drugbank.com/drugs/DB06403
    ApprovedInvestigational

    It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. … In addition, it is approved in the United States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and to improve exercise ability.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid
  5. Drug

    Lidocaine

    go.drugbank.com/drugs/DB00281
    ApprovedInvestigationalVet approved

    It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding … In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety

    Synonyms: 2-(Diethylamino)-2',6'-acetoxylidide, 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamideInternational brands: LidoPain SP, L-Caine
  6. Drug

    Amlodipine

    go.drugbank.com/drugs/DB00381
    ApprovedInvestigational

    Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Amlodipine is commonly used in the treatment of high blood pressure and angina.

    Synonyms: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateInternational brands: Amlodipine 5, Amlodipin-Mepha 5/10
  7. Drug

    Bacitracin

    go.drugbank.com/drugs/DB00626
    ApprovedInvestigationalVet approved

    [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. … Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A.

    Synonyms: Bacitracin AMixtures: Band-aid-S-1, S-Oint TRIPLE ANTIBIOTIC
  8. Drug

    Sodium chlorite

    go.drugbank.com/drugs/DB13210
    Investigational

    Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. … Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].

    Products: Qve - S, V Doctor pure chlorine dioxide
  9. Drug

    Zinc gluconate

    go.drugbank.com/drugs/DB11248
    ApprovedInvestigationalVet approved

    Studies show that zinc may be better absorbed in humans in the gluconate form [A32412], [L2105], however, results from other studies may vary. … It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.

    Mixtures: KORDEL`S EXECUTIVE B TABLET, Citrate De Calcium Plus Vitamine D Et ZincProducts: The Bee, ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion
  10. Drug

    Trimebutine

    go.drugbank.com/drugs/DB09089
    ApprovedInvestigational

    It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. … It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders [A19691].

    Synonyms: 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoatInternational brands: Newbutin SR