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Displaying results 801 - 810 of 8573 in total
  1. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death. … [A18125] Alprazolam was given FDA approval on October 16, 1981.[L6148]

    Products: TAFIL 1.0MG TABL
  2. Drug

    Terbinafine

    go.drugbank.com/drugs/DB00857
    ApprovedInvestigationalVet approved

    [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064]

    Products: DERMAFIN CREAM 10MG/G, TEFIN Terbinafine HCl Spray 10mg/g
  3. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.

    Products: Theochron Srt 100mg, TEOFILINA 300MG
  4. Drug

    Silibinin

    go.drugbank.com/drugs/DB09298
    Investigational

    Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar ratio. … Both in vitro and animal research suggest that silibinin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins.

    Products: HEPATOXIL 150MG CAPSULAS
  5. Drug

    Dimethicone

    go.drugbank.com/drugs/DB11074
    ApprovedInvestigational

    Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. … Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants.

    Mixtures: Isa Knox Ageless Serum Makeup Base 10, Isaknox Ageless Serum Moist Pearl BaseProducts: CUPLATON 100MG CAPSULE, Ovol 160mg Chewable Tablets
  6. Target

    Apoptosis regulator BAX

    go.drugbank.com/bio_entities/BE0010137
    TargetHumans

    Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial

    Polypeptides: Apoptosis regulator BAX
  7. Drug

    Mifepristone

    go.drugbank.com/drugs/DB00834
    ApprovedInvestigational

    As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome. … The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg). Currently under investigation for use in psychotic depression (phase 3 trials).

    Products: MIFEGYNE TABLETS 200MG
  8. Drug

    Tenofovir disoproxil

    go.drugbank.com/drugs/DB00300
    ApprovedInvestigational

    This drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label]. … Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase

    Mixtures: DELSTRIGO FILM COATED TABLET 100MG/300MG/300MG, STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 90 ADETSynonyms: Bis(POC)PMPA, Tenofovir bis(isopropyloxycarbonyloxymethyl) ester
  9. Drug

    Amikacin

    go.drugbank.com/drugs/DB00479
    ApprovedInvestigationalVet approved

    [A39531] Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and Pseudomonas aeruginosa. … [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population

    Products: APALIN 100MG INJECTION (2ML AMP), AMIKACINA 500MG/2ML
  10. Drug

    Tirabrutinib

    go.drugbank.com/drugs/DB15227
    Investigational

    Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).

    Synonyms: ONO-4059 (free base)