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MK-8189
go.drugbank.com/drugs/DB19153InvestigationalMK-8189 is under investigation in clinical trial NCT04624243 (Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)).
Synonyms: 4-PYRIMIDINAMINE, 2-METHYL-6-(((1S,2S)-2-(5-METHYL-2-PYRIDINYL)CYCLOPROPYL)METHOXY)-N-((5-METHYL-1,3,4-THIADIAZOL-2-YL)METHYL)-Pamapimod
go.drugbank.com/drugs/DB19169InvestigationalPamapimod is under investigation in clinical trial NCT05659459 (The KIN-FAST Trial (KIN001 for Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With Sars-cov-2).
Enarodustat
go.drugbank.com/drugs/DB14985InvestigationalEnarodustat is under investigation in clinical trial NCT02581124 (Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease).
Dubermatinib
go.drugbank.com/drugs/DB15187InvestigationalDubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
Denenicokin
go.drugbank.com/drugs/DB12908InvestigationalDenenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Synonyms: L-METHIONYL(HUMAN INTERLEUKIN-21), IL-21 recombinantTandamine
go.drugbank.com/drugs/DB09192ExperimentalTandamine was researched in 1970s as an antidepressant but was never commercialized. Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
go.drugbank.com/drugs/DB01632ApprovedWithdrawnThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Betulinic Acid
go.drugbank.com/drugs/DB12480ApprovedWithdrawnBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Radotinib
go.drugbank.com/drugs/DB12323InvestigationalRadotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.
Medetomidine
go.drugbank.com/drugs/DB11428ExperimentalVet approvedMedetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. … In the United States, it is currently approved for its veterinary use in dogs and distributed by Pfizer Animal Health. In Canada, medetomidine is distributed by Novartis Animal Health.