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Concanamycin A
go.drugbank.com/drugs/DB14062ExperimentalConcanamycin A is an H+-ATPase (vacuolar) inhibitor.
Dimethyl carbate
go.drugbank.com/drugs/DB13204ExperimentalDimethyl carbate is used as an insect repellant.
Aprindine
go.drugbank.com/drugs/DB01429ExperimentalAprindine is a cardiac depressant used in arrhythmias.
QRX-411
go.drugbank.com/drugs/DB17868ExperimentalIt addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.
Spermidine
go.drugbank.com/drugs/DB03566InvestigationalIt is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures.
Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamineSYNB1891
go.drugbank.com/drugs/DB17541Investigational[A256733] SYNB1891 is under investigation in clinical trial NCT04167137 (Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult Subjects).
Gamcemetinib
go.drugbank.com/drugs/DB21624InvestigationalGamcemetinib is under investigation in clinical trial NCT04947579 (A Study of CC-99677 in Participants With Active Ankylosing Spondylitis). … The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor.
ATX-201
go.drugbank.com/drugs/DB05765InvestigationalATX-201 is one of a family of novel compounds that inhibits microtubule polymerization. It is developed by Kythera Biopharmaceuticals, Inc. for the treatment of actinic keratosis. The company announced the decision to discontinue its ATX...
BIIB015
go.drugbank.com/drugs/DB06304InvestigationalBIIB015 is a humanized, IgG1 [immunoglobulin G 1], DM4-Conjugated, anti-cripto, monoclonal antibody. It has been investigated for the treatment of subjects with relapsed or refractory solid tumours.