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SBT101
go.drugbank.com/drugs/DB18139InvestigationalSBT101 is a non-replicating recombinant adeno-associated virus serotype 9 (AAV9) gene therapy vector containing the human adenosine triphosphate (ATP)-binding cassette (ABC) sub-family D member 1 (ABCD1
Opelconazole
go.drugbank.com/drugs/DB18251InvestigationalSynonyms: D-threo-pentitol, 2,5-anhydro-1,3,4-trideoxy-2-c-(2,4-difluorophenyl)-4-((4-(4-(4-(((4-fluorophenyl)amino)carbonyl)phenyl)-1-piperazinyl)-2-methylphenoxy)methyl)-1-(1h-1,2,4-triazol-1-yl)-Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersCC-90001
go.drugbank.com/drugs/DB18445InvestigationalCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsAPPD
go.drugbank.com/drugs/DB18603ExperimentalSynonyms: D-GLYCERO-.ALPHA.-L-TALO-HEPTOFURANURONAMIDE, 5-O-(5-AMINO-5-DEOXY-.BETA., -D-RIBOFURANOSYL)-1,6-DIDEOXY-1-(3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINYL)-6-((4-OXO-4-(((4-(4-(4-(TRIFLUOROMETHOXY)PHENOXY)-1-PIPERIDINYL)PHENYL)METHYL)AMINO)BUTYL)AMINO)-Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesP-42 peptide
go.drugbank.com/drugs/DB18610ExperimentalP-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin protein
Enavogliflozin
go.drugbank.com/drugs/DB18970InvestigationalEnavogliflozin is under investigation in clinical trial NCT06399835 (Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis).
Synonyms: (1s)-1,5-anhydro-1-c-(7-chloro-6-((4-cyclopropylphenyl)methyl)-2,3-dihydro-4-benzofuranyl)-d-glucitol, D-glucitol, 1,5-anhydro-1-c-(7-chloro-6-((4-cyclopropylphenyl)methyl)-2,3-dihydro-4-benzofuranyl)-, (1s)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAminoflavone
go.drugbank.com/drugs/DB19077InvestigationalAminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesFreneslerbart
go.drugbank.com/drugs/DB19080InvestigationalFreneslerbart is under investigation in clinical trial NCT04981717 (A Study to Examine the Efficacy and Safety of Anti-fel D 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic
Synonyms: Anti-cat allergen fel d 1 monoclonal anitbody regn-1908, Immunoglobulin G4 [227-proline], anti-(Felis catus allergen Fel d1) (human monoclonal REGN1908 γ4-chain), disulfide with human monoclonal REGN1908 κ-chain, dimerArketamine
go.drugbank.com/drugs/DB19150InvestigationalArketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).
Synonyms: D-ketamineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSubstance P
go.drugbank.com/drugs/DB19198InvestigationalSubstance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).
Synonyms: Substance P, Neurokinin pCategories: Substance P, antagonists & inhibitors