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Efalizumab
go.drugbank.com/drugs/DB00095ApprovedWithdrawnEfalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. … It was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy (PML).[L43797]
Products: RAPTIVA ®125 MGChoriogonadotropin alfa
go.drugbank.com/drugs/DB00097ApprovedInvestigationalThe primary structure of the alpha-chain of r-hCG is identical to that of the alpha-chain of hCG, FSH and LH. … Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN
Products: OVITRELLE 250 MCG/0,5 ML KULLANIMA HAZIR ŞIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 1 ADETAntithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells. … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients.
Categories: Immunoglobulin G, Increased T Lymphocyte DestructionSynonyms: r-ATG, Lapine T-lymphocyte immune globulinIpratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigationalIpratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent. … [A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption.
Mixtures: BERODUAL® HFA, BERODUAL® HFAProducts: Atrovent ® 0.025% Nebuliser Solution, BRIA®Phenylpropanolamine
go.drugbank.com/drugs/DB00397ApprovedVet approvedWithdrawnPhenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. … It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Mixtures: Sinutab Sa Tab, TERA FCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Adrenergic beta-2 Receptor AgonistsVincristine
go.drugbank.com/drugs/DB00541ApprovedInvestigationalVincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy … It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar.
Mixtures: MEODEX®, MEODEX®Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexFurazolidone
go.drugbank.com/drugs/DB00614InvestigationalVet approvedA nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingSynonyms: 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine, N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidoneGestaclone
go.drugbank.com/drugs/DB21090ExperimentalGestaclone is a small molecule drug. The usage of the INN stem '-clone' in the name indicates that Gestaclone is a hypnotic tranquillizer. Gestaclone has a monoisotopic molecular weight of 370.17 Da.
Phenarsone sulfoxylate
go.drugbank.com/drugs/DB21104ExperimentalPhenarsone sulfoxylate is a small molecule drug. Phenarsone sulfoxylate has a monoisotopic molecular weight of 310.94 Da.
Dimecrotic acid
go.drugbank.com/drugs/DB21126ExperimentalDimecrotic acid is a small molecule drug. Dimecrotic acid has a monoisotopic molecular weight of 222.09 Da.