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Displaying results 8151 - 8160 of 10000 in total
  1. Drug

    Lorpiprazole

    go.drugbank.com/drugs/DB09195
    Approved

    Lorpiprazole is a serotonin antagonist and reuptake inhibitor used for the treatment of major depressive disorder.[A31634] It is a piperazinyl-triazole derivative.[T83]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  2. Drug

    Lubazodone

    go.drugbank.com/drugs/DB09196
    Experimental

    It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist. … Lubazodone (YM-992, YM-35,995) is an arylpiperazine antidepressant which was being developed as a treatment for depression and obsessive compulsive disorder, and reached phase II clinical trials, but was

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Netoglitazone

    go.drugbank.com/drugs/DB09199
    Experimental

    Netoglitazone (MCC-555) is a hypoglycemic agent.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
  4. Drug

    Cirazoline

    go.drugbank.com/drugs/DB09202
    Experimental

    Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2.

    Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor Agonists
  5. Drug

    Synephrine

    go.drugbank.com/drugs/DB09203
    Investigational

    It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine. … The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of some confusion however m-synephrine refers to a related drug more commonly known as phenylephrine.

    Synonyms: p-synephrine
  6. Drug

    Arotinolol

    go.drugbank.com/drugs/DB09204
    Investigational

    It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  7. Drug

    Moxisylyte

    go.drugbank.com/drugs/DB09205
    Approved

    Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist.

    Synonyms: (2-(4-ACETOXY-2-ISOPROPYL-5-METHYLPHENOXY)ETHYL)DIMETHYLAMINE, 6-ACETOXYTHYMOL 2-(DIMETHYLAMINO)ETHYL ETHER
  8. Drug

    Trimazosin

    go.drugbank.com/drugs/DB09206
    Experimental

    Trimazosin is a sympatholytic alpha blocker.

    Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-Ring
  9. Drug

    Pegloticase

    go.drugbank.com/drugs/DB09208
    ApprovedInvestigational

    [L42425] Pegloticase has a longer terminal elimination half-life thanks to the addition of a polyethylene glycol (PEG) group. … [A249980] The PEG group also gives pegloticase a lower potential to induce an immune response.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Pholcodine

    go.drugbank.com/drugs/DB09209
    ApprovedIllicit

    [A31742] Pholcodine is not prescribed in the United States where it is classed as a Schedule I drug. It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008. … Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant.

    Mixtures: Rhynacol F SyrupCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More Rings