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Displaying results 8171 - 8180 of 10000 in total
  1. Drug

    Vusolimogene oderparepvec

    go.drugbank.com/drugs/DB23008
    ApprovedInvestigational

    on a PD-1-blocking antibody-based regimen. … on anti-PD-1 therapy.

    Synonyms: Hsv-1 oncolytic viral strain rp1
  2. Drug

    TRGFT-201

    go.drugbank.com/drugs/DB23064
    ApprovedInvestigational

    Orca-T (allogeneic regulatory T cell immunotherapy with HSPC and T cells-vldq) is a donor-derived allogeneic cell therapy used in matched-donor hematopoietic stem cell transplantation for adults with blood … , regulatory T cells (Tregs), and conventional T cells (Tcons) — administered as sequential infusions.

    International brands: ORCA-T
  3. Drug

    Risvutatug rezetecan

    go.drugbank.com/drugs/DB23560
    Investigational

    Risvutatug rezetecan (GSK5764227) is a novel investigational B7-H3-targeted antibody-drug conjugate. … It is under investigation in clinical trial NCT06885034 (A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers

  4. Drug

    WNY0824

    go.drugbank.com/drugs/DB23606
    Experimental

    [A274253] It is a dual inhibitor of PLK-1 and BRET-4, which have both been found to be involved in CRPC via suppression of AR/MYC-mediated transcription. [A274258] … WNY0824 is a preclinical small molecule drug being investigated for the treatment of Castration-Resistant Prostrate Cancer (CRPC).

    Synonyms: PLK1/BRD4-IN-1
  5. Drug

    Actinium Ac 225 Vipivotide tetraxetan

    go.drugbank.com/drugs/DB23637
    Investigational

    Actinium Ac 225 Vipivotide Tetraxetan is a small molecule drug.

  6. Drug

    Arlocabtagene autoleucel

    go.drugbank.com/drugs/DB24024
    Investigational

    Arlocabtagene Autoleucel is a biologic drug. … Arlocabtagene Autoleucel is under investigation in clinical trial NCT06297226 (Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or

  7. Drug

    Fiztasovimab

    go.drugbank.com/drugs/DB24033
    Investigational

    Fiztasovimab, also known as NPC‐21 and EV2038, is a monoclonal antibody. … [A278004, A278005] NPC-21 is under investigation in clinical trial NCT04225923 (A Study for Kidney Transplant Recipients at High-Risk of Cytomegalovirus Infection).

  8. Drug

    Milsaperidone

    go.drugbank.com/drugs/DB24348
    ApprovedInvestigational

    [L56056] On February 20, 2026, milsaperidone was approved by the FDA for the treatment of Bipolar I Disorder and schizophrenia.[L56059] … [A275426, A202004] Similarly, milsaperidone acts as an antagonist at dopamine D2 and 5-HT2A receptors,[A275427] as well as other adrenergic, dopamine, and serotonin receptor subtypes.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (S)-Hydroxy iloperidone
  9. Drug

    JNJ-64400141

    go.drugbank.com/drugs/DB24373
    Investigational

    JNJ-64400141 is a biologic drug. … JNJ-64400141 is under investigation in clinical trial NCT05242432 (A Study of Adenovirus Serotype 26.Respiratory Syncytial Virus.Pre-Fusion F (Ad26.RSV.preF)-Based Vaccine for Prevention of Respiratory

    Synonyms: Adenovirus Serotype 26.Respiratory Syncytial Virus.Pre-Fusion F
  10. Drug

    Zopapogene imadenovec

    go.drugbank.com/drugs/DB24672
    ApprovedInvestigational

    [L54081] Zopapogene imadenovec is a non-replicating adenoviral vector–based immunotherapy that expresses a fusion antigen from selected regions of HPV-6/11 proteins to elicit an immune response in RRP. … Recurrent respiratory papillomatosis (RRP) is a rare, debilitating disease driven by chronic human papillomavirus (HPV) 6 or 11 infection and characterized by recurrent benign tumors in the respiratory

    Synonyms: under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, DNA (recombinant replication-deficient Gorilla gorilla gorilla adenovirus strain GC4 vector PRGN-2012 human cytomegalovirus promoter plus human papillomavirus 6/11 E2, E4, E6, E7 protein 11 epitope-containing