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Displaying results 8181 - 8190 of 10000 in total
  1. Drug

    R1626

    go.drugbank.com/drugs/DB05060
    Experimental

    R1626 is one of a new class of hepatitis C therapies called polymerase inhibitors.

  2. Drug

    Thalagen

    go.drugbank.com/drugs/DB17714
    Experimental

    It is being investigated for the treatment of beta-thalassemia.[L46168] … It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral vector encoding the normal human beta-globin gene.

  3. Drug

    Isospaglumic acid

    go.drugbank.com/drugs/DB19650
    Investigational

    Isospaglumic acid has a monoisotopic molecular weight of 304.09 Da. … Isospaglumic acid is under investigation in clinical trial NCT06800274 (Clinical and Biological Evaluation of NAAGA Versus Azelastine Eye Drops in Allergic Subjects With Tear Film Dysfunction).

  4. Drug

    (4R)-limonene

    go.drugbank.com/drugs/DB08921
    Investigational

    As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant

  5. Drug

    Bevurogant

    go.drugbank.com/drugs/DB21507
    Experimental

    Bevurogant has a monoisotopic molecular weight of 532.2 Da. … The usage of the INN stem '-rogant' in the name indicates that Bevurogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist.

  6. Drug

    Izumerogant

    go.drugbank.com/drugs/DB21604
    Experimental

    Izumerogant has a monoisotopic molecular weight of 495.11 Da. … The usage of the INN stem '-rogant' in the name indicates that Izumerogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist.

  7. Drug

    Glovadalen

    go.drugbank.com/drugs/DB21709
    Investigational

    Glovadalen has a monoisotopic molecular weight of 475.14 Da. … Glovadalen is under investigation in clinical trial NCT06970301 (A Study to Assess the Safety and Tolerability, and Pharmacokinetics of UCB0022 in Healthy Caucasian, Japanese, and Chinese Participants)

  8. Drug

    Putrescine

    go.drugbank.com/drugs/DB01917
    Investigational

    Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme. … Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines.

  9. Drug

    Phosphorus P-32

    go.drugbank.com/drugs/DB14551
    Investigational

    Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. … Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular

  10. Drug

    Englumafusp alfa

    go.drugbank.com/drugs/DB19341
    Investigational

    and in Combination With Glofitamab Following a Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/refractory B-cell Non-hodgkin's Lymphoma). … Englumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab

    Synonyms: humanized immunoglobulin G1-kappa anti-(human B-lymphocyte antigen CD19) modified heterodimer where the heavy and light chain variable regions of one arm have been substituted by three subunits of human