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Displaying results 811 - 820 of 10000 in total
  1. Drug

    Quinacrine

    go.drugbank.com/drugs/DB01103
    Investigational

    An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. … It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine, 3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine
  2. Drug

    AZD-5153

    go.drugbank.com/drugs/DB17018
    Investigational

    Synonyms: 2-piperazinone, 4-(2-(4-(1-(3-methoxy-1,2,4-triazolo(4,3-b)pyridazin-6-yl)-4-piperidinyl)phenoxy)ethyl)-1,3-dimethyl-, (3r)-Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Cycloserine

    go.drugbank.com/drugs/DB00260
    ApprovedInvestigational

    Antibiotic substance produced by Streptomyces garyphalus.

    Synonyms: D-4-amino-3-isoxazolidone, D-4-amino-3-isoxazolidinoneCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Pentosan polysulfate

    go.drugbank.com/drugs/DB00686
    ApprovedInvestigational

    Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.

    Synonyms: (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULFATE, (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULPHATEProducts: MISURE ® GEL, MENTOSANIL®
  5. Drug

    WSD-0922

    go.drugbank.com/drugs/DB17170
    Investigational

    Synonyms: (r)-6-((3,3-difluoro-1-methylpiperidin-4-yl)oxy)-n-(3-ethynyl-2-fluorophenyl)-7-methoxyquinazolin-4-amine-Salts: (R)-6-((3,3-Difluoro-1-Methylpiperidine-4-Yl)Oxy-N-(3-Ethynyl-2-Fluorophenyl)-7-Methoxyquinazolin-4-Amine Fumerate
  6. Drug

    Methylprednisolone

    go.drugbank.com/drugs/DB00959
    ApprovedInvestigationalVet approved

    Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s. … [A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957.

    Mixtures: Physicians EZ Use M-pred, Physicians EZ Use M-predCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inducers
  7. Drug

    1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE

    go.drugbank.com/drugs/DB08746
    Experimental

    Synonyms: 1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE
  8. Drug

    Lenalidomide

    go.drugbank.com/drugs/DB00480
    ApprovedInvestigational

    [A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. … [A714, A228543] Thalidomide and its analogues, including lenalidomide, are referred to as immunomodulatory imide drugs (also known as cereblon modulators), which are a class of immunomodulatory drugs that

    Synonyms: 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  9. Drug

    JQ1

    go.drugbank.com/drugs/DB17021
    Experimental

    First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]

    Synonyms: (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate, Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate
  10. Drug

    4-amino-N-[4-(benzyloxy)phenyl]butanamide

    go.drugbank.com/drugs/DB07104
    Experimental

    Synonyms: 4-amino-N-[4-(benzyloxy)phenyl]butanamide