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Displaying results 811 - 820 of 10000 in total
  1. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme … increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis and bone fractures later in life.

    Mixtures: VIMOVO 500MG/20MG MODIFIED-RELEASE TABLETSInternational brands: ES-OD
  2. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    in the epithelium[A32373]. … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.

    Mixtures: Multivit Et Fer Ampoules Et Comprimes, Dynam Ampoule Et TabletSynonyms: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
  3. Drug

    Phenoxymethylpenicillin

    go.drugbank.com/drugs/DB00417
    ApprovedInvestigationalVet approved

    An orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by penicillin G­-sensitive microorganisms … Phenoxymethylpenicillin has also be used in some cases as prophylaxis against susceptible organisms.

    International brands: Pen-V, Apo-Pen-VKProducts: Pen Vee Sus 180mg, Pen-vee Suspension 180mg/5ml
  4. Drug

    Pergolide

    go.drugbank.com/drugs/DB01186
    ApprovedVet approvedWithdrawn

    The drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. … It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors.

    Products: PERGOLIDE EG
  5. Drug

    Ziprasidone

    go.drugbank.com/drugs/DB00246
    ApprovedInvestigational

    [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to treat manic episodes in bipolar disorder although the mechanism of action is unknown. … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525]

    Products: ZELDOX 10MG/ML, ZELDOX IM ENJ. SOL. ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADET
  6. Drug

    Ceftobiprole medocaril

    go.drugbank.com/drugs/DB14733
    Approved

    [L50467] It received its first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and was subsequently approved in the United States with additional indications … for skin and skin structure infections and bacteremia in April 2024.

    Products: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  7. Drug

    Lacidipine

    go.drugbank.com/drugs/DB09236
    Approved

    It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure. … Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity.

    Products: LACIDIPINA EG
  8. Drug

    Vancomycin

    go.drugbank.com/drugs/DB00512
    ApprovedInvestigational

    Such an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196].

    Products: VANCOMICINA BONISCONTRO E GAZZONE, VANCOCINA CP 500MG
  9. Drug

    Miconazole

    go.drugbank.com/drugs/DB01110
    ApprovedInvestigationalVet approved

    Despite having been in clinical use for an extended period, resistance to miconazole among susceptible organisms is relatively low.[A203636] … [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream.

    Mixtures: Monistat 3 Combination Pack 3-Day in Pre-Filled Applicators, Monistat 3 Combination Pack 3-Day in Pre-Filled ApplicatorsProducts: MICONOR 100MG OVULES, Monistat 7 Sup Vag 100mg
  10. Drug

    Dexlansoprazole

    go.drugbank.com/drugs/DB05351
    Approved

    [A19566, A19568, A178084, A174244] Dexlansoprazole inhibits the final step in gastric acid production by blocking the (H+, K+)-ATPase enzyme.[L48827]

    Products: DELAXISE 30 MG EC RETARD TABLET, 30 ADET, DELAXISE 60 MG EC RETARD TABLET, 30 ADET