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Allopurinol riboside
go.drugbank.com/drugs/DB17738ExperimentalAllopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at the 1-position.
Synonyms: 4h-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-.beta.-d-ribofuranosyl-EF-022
go.drugbank.com/drugs/DB17768InvestigationalEF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Synonyms: Modified vitamin D binding protein, Modified Vitamin D Binding Protein Macrophage ActivatorLinafexor
go.drugbank.com/drugs/DB18031InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGunagratinib
go.drugbank.com/drugs/DB18191ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesACTX-401
go.drugbank.com/drugs/DB18504ExperimentalACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human immunoglobulin u-binding protein 2 cDNA.
Elzasonan
go.drugbank.com/drugs/DB18969InvestigationalElzasonan is under investigation in clinical trial NCT00275197 (A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD)).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSevasemten
go.drugbank.com/drugs/DB18983InvestigationalSevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMethylone
go.drugbank.com/drugs/DB19192InvestigationalMethylone is under investigation in clinical trial NCT05741710 (A Study to Assess the use of Methylone in the Treatment of PTSD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSofpironium
go.drugbank.com/drugs/DB19325ApprovedSofpironium is a "soft" anticholinergic analog of glycopyrronium that has been modified with a readily hydrolyzable ester moiety. Soft drugs are designed to reduce systemic toxicity while enhancing local efficacy by employing retrometabo...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsInterferon gamma-1b
go.drugbank.com/drugs/DB00033ApprovedInvestigationalHuman Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purificat...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors