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Displaying results 8251 - 8260 of 10000 in total
  1. Drug

    BBIBP-CorV

    go.drugbank.com/drugs/DB15807
    Investigational

    Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques[A219763]. … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.

    Categories: Complex Mixtures
  2. Drug

    Zeteletinib

    go.drugbank.com/drugs/DB21491
    Investigational

    Zeteletinib is under investigation in clinical trial NCT03780517 (Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors). … The usage of the INN stem '-tinib' in the name indicates that Zeteletinib is a tyrosine kinase inhibitor.

  3. Drug

    Xeruborbactam

    go.drugbank.com/drugs/DB21512
    Investigational

    Xeruborbactam is under investigation in clinical trial NCT07104162 (A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal Impairment). … The usage of the INN stem '-bactam' in the name indicates that Xeruborbactam is a ẞ-lactamase inhibitor.

  4. Drug

    Gridegalutamide

    go.drugbank.com/drugs/DB21593
    Investigational

    Gridegalutamide is under investigation in clinical trial NCT04428788 (Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer). … The usage of the INN stem '-lutamide' in the name indicates that Gridegalutamide is a non-steroid antiandrogen.

  5. Drug

    Docirbrutinib

    go.drugbank.com/drugs/DB21606
    Investigational

    Docirbrutinib is under investigation in clinical trial NCT05602363 (AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma). … The usage of the INN stem '-brutinib' in the name indicates that Docirbrutinib is a agammaglobulinaemia tyrosine kinase (Bruton tyrosine kinase) inhibitor.

  6. Drug

    Lomedeucitinib

    go.drugbank.com/drugs/DB21649
    Investigational

    Lomedeucitinib is under investigation in clinical trial NCT05730725 (A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe Psoriasis). … The usage of the INN stem '-citinib' in the name indicates that Lomedeucitinib is a Janus kinase inhibitor.

  7. Drug

    Bimokalner

    go.drugbank.com/drugs/DB21717
    Investigational

    Bimokalner is under investigation in clinical trial NCT06521190 (ACOU085 for Hearing Loss Prevention in Testicular Cancer Patients Receiving Cisplatin). … The usage of the INN stem '-kalner' in the name indicates that Bimokalner is a opener of calcium-activated (maxi-K) K+-channel.

  8. Drug

    RO7830698

    go.drugbank.com/drugs/DB33974
    Experimental

    RO7830698 is under investigation in clinical trial NCT07822334 (A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease).

  9. Drug

    Paxalisib

    go.drugbank.com/drugs/DB15186
    Investigational

    GDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).

    Synonyms: 5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[3,4-e]purin-2-yl)pyrimidin-2-amine
  10. Drug

    MEDI6012

    go.drugbank.com/drugs/DB14833
    Investigational

    Recombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction