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Displaying results 8261 - 8270 of 10000 in total
  1. Drug

    Ceftiofur

    go.drugbank.com/drugs/DB11485
    ExperimentalVet approved

    Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. … It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product.

  2. Drug

    Incadronic acid

    go.drugbank.com/drugs/DB06255
    Experimental

    Incadronate, or YM-175,[A202769] is a nitrogen containing bisphosphonate.

    International brands: Yin Fu
  3. Drug

    TST10088

    go.drugbank.com/drugs/DB05151
    Experimental

    TST10088 is a recombinant variant of a plant toxin belonging to the family of class II ribosome inactivating proteins. … These molecules efficiently kill cells by activating preprogrammed death pathways known as apoptosis.

  4. Drug

    PX-12

    go.drugbank.com/drugs/DB05448
    Investigational

    Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced … PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits

  5. Drug

    Lysergic acid diethylamide

    go.drugbank.com/drugs/DB04829
    IllicitInvestigational

    Many emotionally intense experiences can lead to flashbacks when a person is reminded acutely of the original experience. … However, not all published case reports of chronic flashbacks appear to describe an anxious hyper-vigilant state reminiscent of post-traumatic stress disorder.

    Synonyms: D-lysergic acid diethylamide, N,N-diethyl-D-lysergamide
  6. Drug

    Allocetra

    go.drugbank.com/drugs/DB16424
    Investigational

    Allocetra is a novel therapy where billions of early apoptotic cells are infused into the bloodstream of a patient, using the body's own natural regulation mechanisms to rebalance an unbalanced immune … these early apoptotic Allocetra cells and thus result in the macrophages and dendritic cells releasing fewer cytokine alert signals so that the immune system is rebalanced back to normal -- averting a

  7. Drug

    ARC183

    go.drugbank.com/drugs/DB05124
    Experimental

    ARC183 is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity … The key advantage of ARC183 compared to other thrombin inhibitors is its rapid onset of action and short half-life, giving it the potential to be an ideal agent for medical procedures that require rapid

  8. Drug

    KP-1461

    go.drugbank.com/drugs/DB05644
    Investigational

    Designated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases. … KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue.

  9. Drug

    Mepiprazole

    go.drugbank.com/drugs/DB09197
    Experimental

    Mepiprazole is a minor tranquilizer with a phenylpiperazine structure. It is a pyrazolyl-alkyl-piperazine derivative. … It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake and induce the release of serotonin, dopamine, and norepinephrine to varying extents.

  10. Drug

    Multipotent adult arogenitor cells

    go.drugbank.com/drugs/DB15742
    Investigational

    The cells for creation of the product are isolated from a qualified donor and expanded on a large scale and then frozen until use. After administration, the cells are cleared from the body over time. … MultiStem is an intravenously-administered, off-the-shelf proprietary product developed which comprises Multipotent Adult Progenitor Cells (MAPCs).