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Deferasirox
go.drugbank.com/drugs/DB01609ApprovedInvestigationalDeferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Products: RASIROX® 250MG, Exjade Dispersible Tablet 250mgTocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigational[L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December 2022, respectively. … [L12789] It was later approved by Health Canada on 30 April 2010.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Actemra Concentrate for Solution for Infusion 20mg/ml, ACTEMRA® CONCENTRADO PARA INFUSION 200 MG/10MLLevamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer. … [L6232] Prior to this, levamisole was used as an antirheumatic therapy in the 1970s and 1980s for patients with rheumatoid arthritis.
Categories: Antiparasitic Products, Insecticides and RepellentsProducts: OBAT CACING NO.17 KAM CEK SAN, Ergamisol Tab 50mgEtoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalEtoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. … Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside), 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-oneBuclizine
go.drugbank.com/drugs/DB00354ApprovedIt was manufactured by Stuart Pharms and initially approved by the FDA in 1957. … Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging to the _piperazine derivative_ family of drugs.
Products: BUCLIZINA CLORHIDRATO 25MGAllopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalIt was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705
Products: Nu-allopurinol, CLINT TABLET 100MGTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceuticaland differentiation. … [A257689] It has been used in dermatology for many years to treat various skin conditions ranging from acne to wrinkles [A257474,A258185] and activates nuclear receptors to regulate epithelial cell growth
Mixtures: Throwers Pbc No. 1, Clindamycin Phosphate and TretinionCategories: Cell Stimulants and Proliferants, Antineoplastic and Immunomodulating AgentsGlucosamine
go.drugbank.com/drugs/DB01296Approved[A231894,A232289] It is currently not approved as a prescription product by the FDA, but is widely available over the counter. … Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation.
Mixtures: Bee Venom Joint And Bone Therapy Drops, Blackmores Joint Formula with Glucosamine and ChondroitinCategories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Antiinflammatory and Antirheumatic ProductsVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease and hemophilia A. It was first approved by the FDA in 2015. … It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII).
Mixtures: Haemate P Powder and solvent for solution for injection or infusion, Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for InjectionCategories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalDue to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life. … [A183782,L8648] This drug relieves undesirable urinary symptoms, increasing the quality of life for patients affected by OAB. It is often used as first-line therapy for OAB.[A185990]
Categories: Genito Urinary System and Sex Hormones, Drugs for Urinary Frequency and IncontinenceProducts: Ditropan Syrup 1mg/ml, OXYBUTYNIN HEXAL 2.5MG