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Displaying results 821 - 830 of 7379 in total
  1. Drug

    Biotin

    go.drugbank.com/drugs/DB00121
    ApprovedInvestigationalNutraceutical

    A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.

    Mixtures: Super Daily No 2, Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHAProducts: Tk-nax
  2. Drug

    (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol

    go.drugbank.com/drugs/DB06943
    Experimental

    (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a solid. This compound belongs to the benzenesulfonamides. … These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. This substance is known to target disintegrin and metalloproteinase domain-containing protein 17.

    Synonyms: (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol
  3. Drug

    Aluminum chlorohydrate

    go.drugbank.com/drugs/DB11573
    Approved

    It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.

    Mixtures: PERS-MANT %19 + %2 JEL (30 G)Products: Old Spice On-The-Go No Melt Clean Scent, Antiperspirant Above One By Sport Men
  4. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    [A178948,A178969] Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. … [A178948] The topical form of brimonidine was approved by the FDA in August 2013 for the symptomatic treatment of persistent facial erythema of rosacea in adults.

    Mixtures: TQ BRIMOLOL® SOLUCION OFTALMICA, BRIMOCHEK -T EYE DROPS SOLUTIONProducts: TQ BRIMOFTAL®SOLUCION OFTALMICA, ALPHAGAN® Z
  5. Drug

    (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE

    go.drugbank.com/drugs/DB08186
    Experimental

    Synonyms: (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE
  6. Drug

    Pralatrexate

    go.drugbank.com/drugs/DB06813
    ApprovedInvestigational

    [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes. … [A246703] As such, pralatrexate is thought to have a better therapeutic window compared to other antifolate analogs due to the novel target of RFC.

    Synonyms: (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid
  7. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.

    Synonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamideProducts: Nu-leflunomide
  8. Drug

    Homosalate

    go.drugbank.com/drugs/DB11064
    Approved

    There are no reported adverse effects from homosalate. … Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light.

    Mixtures: Bull Frog SPF 50, Bull Frog Kids Mist 50
  9. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Later they continued to be investigated for use in heart failure throughout the 1970-1980s. … [A235865] The use of atenolol may need to be based on more patient factors than hypertension alone.[A235850,A235855,A235860,A235865]

    Mixtures: NIFETEX-TR CAPSULE, ATENOLOL CO RATIO 100/25MGProducts: MIN-T, Nu-atenol Tab 50mg
  10. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    Tramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the … These pathways are complementary and synergistic, improving tramadol's ability to modulate the perception of and response to pain.

    Mixtures: STADIUM-T, TRALIC TPCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome