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Aranidipine
go.drugbank.com/drugs/DB09229ExperimentalIt is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate. … Aranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingBenidipine
go.drugbank.com/drugs/DB09231InvestigationalBenidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. … It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: CONIEL 4 MG TABLET, 30 ADET, BENIPIN 4 MG FILM KAPLI TABLET, 30 ADETDarodipine
go.drugbank.com/drugs/DB09234ExperimentalDarodipine is a calcium channel blocker.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingHydracarbazine
go.drugbank.com/drugs/DB09243ExperimentalHydracarbazine is a pyridazine that has found use as an antihypertensive agent [A19790] It was once marketed in France under the tradename Normatensyl.
Toloxatone
go.drugbank.com/drugs/DB09245ExperimentalToloxatone is an antidepressant agent, the first ever use of which was in France, 1984. It acts as a selective and reversible inhibitor of monoamine oxidase-A (MOA) [L1388].
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedDextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. … The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units.
Mixtures: Best Choice Eye Drops Advanced Relief, SK Advanced Relief Eye DropsCategories: Compounds used in a research, industrial, or household settingTegafur
go.drugbank.com/drugs/DB09256ApprovedInvestigationalTegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. … It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with [DB09257] and [DB03209], or along with [DB00544] as [DB09327].
Mixtures: TS-ONE CAPSULE 20, TS-ONE CAPSULE 20Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexCertoparin
go.drugbank.com/drugs/DB09261ApprovedCertoparin is part of the heparins of low molecular weight that presents high activity against the coagulation factor Xa. It is normally used to prevent deep venous thrombosis.
Imidafenacin
go.drugbank.com/drugs/DB09262InvestigationalIt is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical. … Imidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates