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Displaying results 8321 - 8330 of 10000 in total
  1. Drug

    Emrusolmin

    go.drugbank.com/drugs/DB13927
    Investigational

    Emrusolmin restores hippocampal synaptic and transcriptional plasticity as well as spatial memory in a mouse model for Alzheimer's disease, when given orally before or after the onset of pathology.

  2. Drug

    GSK-945237

    go.drugbank.com/drugs/DB15345
    Investigational

    GSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose … and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237 and Moxifloxacin on QTc.).

  3. Drug

    Gevokizumab

    go.drugbank.com/drugs/DB12119
    Investigational

    Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.

  4. Drug

    Fuzapladib

    go.drugbank.com/drugs/DB19478
    Experimental

    Fuzapladib is a small molecule drug. The usage of the INN stem '-pladib' in the name indicates that Fuzapladib is a phospholipase A2​ inhibitor.

  5. Drug

    Ponalrestat

    go.drugbank.com/drugs/DB19717
    Experimental

    Ponalrestat is a small molecule drug. The usage of the INN stem '-restat' in the name indicates that Ponalrestat is a aldose reductase inhibitor.

  6. Drug

    Vatinoxan

    go.drugbank.com/drugs/DB19781
    Experimental

    Vatinoxan is a small molecule drug. The usage of the INN stem '-oxan(e)' in the name indicates that Vatinoxan is a benzodioxane derivative. Vatinoxan has a monoisotopic molecular weight of 418.17 Da.

  7. Drug

    Flesinoxan

    go.drugbank.com/drugs/DB19853
    Experimental

    Flesinoxan is a small molecule drug. The usage of the INN stem '-oxan(e)' in the name indicates that Flesinoxan is a benzodioxane derivative.

  8. Drug

    Solimastat

    go.drugbank.com/drugs/DB19872
    Experimental

    Solimastat is a small molecule drug. The usage of the INN stem '-mastat' in the name indicates that Solimastat is a matrix metalloproteinase inhibitor.

  9. Drug

    Tametraline

    go.drugbank.com/drugs/DB19888
    Experimental

    Tametraline is a small molecule drug. The usage of the INN stem '-traline' in the name indicates that Tametraline is a serotonin reuptake inhibitor.

  10. Drug

    Umibecestat

    go.drugbank.com/drugs/DB19898
    Experimental

    Umibecestat is a small molecule drug. The usage of the INN stem '-becestat' in the name indicates that Umibecestat is a beta secretase inhibitor.