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Inaxaplin
go.drugbank.com/drugs/DB21521InvestigationalInaxaplin is under investigation in clinical trial NCT06794996 (Phase 2b Open-label Study of Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease).
Freneslerbart
go.drugbank.com/drugs/DB19080InvestigationalFreneslerbart is under investigation in clinical trial NCT04981717 (A Study to Examine the Efficacy and Safety of Anti-fel D 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic
VH3739937
go.drugbank.com/drugs/DB25287InvestigationalVH3739937 is under investigation in clinical trial NCT06533280 (VH3739937 Phase 1 Multiple Ascending Dose (MAD) Study in Healthy Volunteers Including Relative Bioavailability (RBA), Optional Food Effect
Tanogitran
go.drugbank.com/drugs/DB21367InvestigationalTanogitran is under investigation in clinical trial NCT02254057 (Tolerability and Pharmacokinetics/-Dynamics of Single Rising Doses BIBT 986 BS in Healthy Male Subjects).
Rosabulin
go.drugbank.com/drugs/DB20161InvestigationalRosabulin is under investigation in clinical trial NCT00276913 (A Phase I Study of STA-5312 in Subjects With Advanced or Metastatic Solid Tumors).
Crelosidenib
go.drugbank.com/drugs/DB21642InvestigationalCrelosidenib is under investigation in clinical trial NCT04603001 (Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations).
Mephenytoin
go.drugbank.com/drugs/DB00532ApprovedWithdrawnThese are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. Mephenytoin is known to target sodium channel protein type 5 subunit alpha.
AV-COVID-19
go.drugbank.com/drugs/DB15802InvestigationalAs of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine. … The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration.
Alfaxalone
go.drugbank.com/drugs/DB11371ExperimentalVet approvedIt is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats.
Sulbutiamine
go.drugbank.com/drugs/DB13416InvestigationalThe chronic administration of the drug has demonstrated to improve long term memory formation in mice. … While its other uses include improvement of erectile dysfunction and reduction of psycho-behavioural inhibition, sulbutiamine showed evidence of modulatory effect on dopaminergic and glutamatergic cortical