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Lefamulin
go.drugbank.com/drugs/DB12825ApprovedLefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia. A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus. Lefamulin is av...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTrofosfamide
go.drugbank.com/drugs/DB12902InvestigationalTrofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOtilonium
go.drugbank.com/drugs/DB13500InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCloranolol
go.drugbank.com/drugs/DB13508ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesDeltamethrin
go.drugbank.com/drugs/DB13600ExperimentalCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsPentifylline
go.drugbank.com/drugs/DB13634ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSemustine
go.drugbank.com/drugs/DB13647InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalAldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 ge...
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigationalHuman growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during c...
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InducersGemtuzumab ozogamicin
go.drugbank.com/drugs/DB00056ApprovedInvestigationalGemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp. calichensis. Gemtuzuma...