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Displaying results 831 - 840 of 10000 in total
  1. Drug

    Leuprolide

    go.drugbank.com/drugs/DB00007
    ApprovedInvestigational

    [A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the tradename Lupron™ by Abbvie Endocrine Inc. … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use.

    Products: LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE, LUCRIN DEPOT-3,75 MG IM/SC ENJEKSIYONLUK FLAKON, 1 ADET
  2. Indication

    Inhalational Anthrax

    go.drugbank.com/conditions/DBCOND0065198
    Drugs: Anthrax immune globulin human · Cethromycin · Ciprofloxacin · Doxycycline · Levofloxacin · Obiltoxaximab +1 more
    Synonyms: Pneumonia in anthrax, Pneumonia in anthrax (disorder)
  3. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    [A262681] It was granted approval by Health Canada in September 2010.[L49206] … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008.

    Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEProducts: LASOMID IN, BENVIDA 10 MG/ML IV INFUZYON COZELTISI, 20 ML
  4. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine].

    Products: Zaditen konservierungsmittelfrei 0,025% - Augentropfen in Einzeldosisbehältnissen, Ketotifen Stulln 250 Mikrogramm/ml Augentropfen im Einzeldosisbehältnis
  5. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. … [A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957.

    Mixtures: Maux De Gorge Et De LA Toux Extra-fort, Cold & Flu-IN-oneCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist
  6. Drug

    Daratumumab

    go.drugbank.com/drugs/DB09331
    ApprovedInvestigational

    [A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. … [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs.

    Products: Darzalex IV
  7. Drug

    Colistin

    go.drugbank.com/drugs/DB00803
    ApprovedInvestigational

    It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Rican Premix Powder 1,900 IU/mg, Collis Colistin 1,500,000 IU/g Water Soluble Powder
  8. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    into therapy in the early 1960s. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced

    Products: Isoptin Inj 2.5mg/ml, ISOPTIN IV INFUZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 ADET
  9. Indication

    Relapsed Multiple Myeloma

    go.drugbank.com/conditions/DBCOND0031510
    Drugs: Belantamab mafodotin · Carfilzomib · Ciltacabtagene autoleucel · Daratumumab · Dexamethasone · Elranatamab +8 more
    Synonyms: Multiple Myeloma in Relapse
  10. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide