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Displaying results 831 - 840 of 10000 in total
  1. Target

    Beta-glucosidase A

    go.drugbank.com/bio_entities/BE0001804
    TargetPaenibacillus polymyxa

    BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.

    Polypeptides: Beta-glucosidase A
  2. Target

    GABA(A) Receptor

    go.drugbank.com/bio_entities/BE0004797
    TargetHumans

    GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit

    Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activity
  3. Target

    Apolipoprotein A-IV

    go.drugbank.com/bio_entities/BE0009049
    TargetHumans

    Apoa-IV is a major component of HDL and chylomicrons … May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.

    Polypeptides: Apolipoprotein A-IV
  4. Target

    HSP40, subfamily A

    go.drugbank.com/bio_entities/BE0009270
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: HSP40, subfamily ASynonyms: HSP40, subfamily A, putative
  5. Drug

    Lanreotide

    go.drugbank.com/drugs/DB06791
    ApprovedInvestigational

    Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome … This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg, Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 60 mg
  6. Drug

    Hydrocortisone succinate

    go.drugbank.com/drugs/DB14545
    ApprovedInvestigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersProducts: A-hydrocort, A-hydrocort Inj 250mg/2ml
  7. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for rehydration, nutrition, and replenishment of electrolytes. … Potassium is an essential nutrient, like [Calcium] and [Magnesium]. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans.

    Mixtures: One A Day Tab, Extra Once A DaySynonyms: K
  8. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.

    Mixtures: COSOPT SINE 20MG/ML+5MG/ML, COSOPT SINE 20MG/ML+5MG/MLCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  9. Drug

    Insulin glargine

    go.drugbank.com/drugs/DB00047
    ApprovedInvestigational

    If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … Insulin is also used in the treatment of Type 2 Diabetes (T2D), another form of diabetes mellitus that is a slowly progressing metabolic disorder caused by a combination of genetic and lifestyle factors

    International brands: Lantus RMixtures: Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen, SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML
  10. Drug

    Aztreonam

    go.drugbank.com/drugs/DB00355
    ApprovedInvestigational

    A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. … It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid, 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid