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Displaying results 831 - 840 of 2828 in total
  1. Drug

    KB001

    go.drugbank.com/drugs/DB05222
    Investigational

    KB001 is a Humaneered™ PEGylated monoclonal antibody fragment for the treatment of life-threatening Pseudomonas aeruginosa infections, a common problem of cystic fibrosis and mechanically ventilated patients.

  2. Drug

    Tariquidar

    go.drugbank.com/drugs/DB06240
    Investigational

  3. Drug

    Black cohosh

    go.drugbank.com/drugs/DB13975
    ApprovedInvestigational

    Black cohosh (Actaea racemosa or Cimicifuga racemosa), a member of the buttercup family, is a perennial plant which native to North America. Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheu...

    Categories: Genito Urinary System and Sex Hormones, Complex Mixtures
  4. Target

    Solute carrier family 15 member 2

    go.drugbank.com/bio_entities/BE0001134
    TransporterTargetHumans

    Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity). Also able to transport carnosine (PubMed:31073693). … Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:16434549, PubMed:18367661, PubMed:7756356).

    Synonyms: Peptide transporter 2, Oligopeptide transporter, kidney isoformFunction: dipeptide transmembrane transporter activity
  5. Drug

    Desogestrel

    go.drugbank.com/drugs/DB00304
    ApprovedInvestigational

    [T521] Desogestrel is now produced semi-synthetically from naturally occurred plant steroids.[F4127] In the US, desogestrel is found only in combination with [ethinyl estradiol].

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  6. Target

    Polycomb protein SCMH1

    go.drugbank.com/bio_entities/BE0004637
    TargetHumans

    Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes

    Synonyms: Sex comb on midleg homolog 1
  7. Drug

    Simoctocog alfa

    go.drugbank.com/drugs/DB09108
    Approved

    Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an ant...

  8. Drug

    Odesivimab

    go.drugbank.com/drugs/DB15900
    ApprovedInvestigational

    [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection.

  9. Target

    Solute carrier family 15 member 1

    go.drugbank.com/bio_entities/BE0001018
    TransporterTargetHumans

    Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. … Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system (PubMed:15521010, PubMed:9835627)

    Synonyms: Peptide transporter 1, Oligopeptide transporter, small intestine isoformFunction: dipeptide transmembrane transporter activity
  10. Drug

    Clamikalant

    go.drugbank.com/drugs/DB20383
    Experimental

    The usage of the INN stem '-kalant' in the name indicates that Clamikalant is a potassium channel blocker. Clamikalant has a monoisotopic molecular weight of 471.07 Da.

    Categories: Membrane Transport Modulators