Solute carrier family 15 member 2

BE0001134ProteinHumansSLC15A2

Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:16434549, PubMed:18367661, PubMed:7756356). It is acted on by 45 drugs in DrugBank.

Gene name
SLC15A2
UniProtKB entry
Q16348Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
729 residues · 81,783 Da
Also known as
Kidney H(+)/peptide cotransporter · Oligopeptide transporter, kidney isoform · PEPT2 · Peptide transporter 2

Resolves to

Protein
UniProtQ16348UniProt nameS15A2_HUMAN
Gene
HGNCHGNC:10921NCBI Gene6565GenBank999213GeneCardsSLC15A2
Pharmacology
IUPHAR/GtoPdb985KEGGhsa:6565
Structure
PDB6EZIPDB7PMYPDB9UDC
Drugs

What you can answer from here — as of September 07, 2019

45DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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81+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 15 member 2, how selective are they, and which programs against it are still in active trials?

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