Solute carrier family 15 member 1

BE0001018ProteinHumansSLC15A1

Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. It is acted on by 58 drugs in DrugBank.

Gene name
SLC15A1
UniProtKB entry
P46059Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
708 residues · 78,805 Da
Also known as
Intestinal H(+)/peptide cotransporter · Oligopeptide transporter, small intestine isoform · PEPT1 · Peptide transporter 1

Resolves to

Protein
UniProtP46059UniProt nameS15A1_HUMAN
Gene
HGNCHGNC:10920NCBI Gene6564GenBank773588GeneCardsSLC15A1
Pharmacology
IUPHAR/GtoPdb984KEGGhsa:6564
Structure
PDB7PMWPDB7PMXPDB7PN1
Drugs

What you can answer from here — as of September 07, 2019

58DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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150+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 15 member 1, how selective are they, and which programs against it are still in active trials?

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