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Displaying results 8431 - 8440 of 10000 in total
  1. Drug

    PR006

    go.drugbank.com/drugs/DB17002
    Experimental

    PR006 is a non-replicating recombinant adeno-associated virus serotype 9 containing the progranulin gene. It is being investigated for the treatment of dementia.

  2. Drug

    AZD-5153

    go.drugbank.com/drugs/DB17018
    Investigational

    Synonyms: 2-piperazinone, 4-(2-(4-(1-(3-methoxy-1,2,4-triazolo(4,3-b)pyridazin-6-yl)-4-piperidinyl)phenoxy)ethyl)-1,3-dimethyl-, (3r)-Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    IMCY-0141

    go.drugbank.com/drugs/DB17019
    Investigational

    IMCY-0141 is a synthetic peptide based on MOG (Myelin Oligodendrocyte Glycoprotein), a dominant autoantigen, designed to stop the progression of multiple sclerosis (MS) and the destruction of the myelin

  4. Drug

    ABT-737

    go.drugbank.com/drugs/DB17023
    Experimental

    An inhibitor of members of the Bcl‑2 family of apoptosis regulators.[A252977]

    Synonyms: Benzamide, 4-(4-((4'-chloro(1,1'-biphenyl)-2-yl)methyl)-1-piperazinyl)-n-((4-(((1r)-3-(dimethylamino)-1-((phenylthio)methyl)propyl)amino)-3-nitrophenyl)sulfonyl)-Categories: Proto-Oncogene Proteins c-bcl-2, Heterocyclic Compounds, 1-Ring
  5. Drug

    Go-6976

    go.drugbank.com/drugs/DB17029
    Experimental

    An inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]

    Synonyms: 12h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring
  6. Drug

    JTC-801 free base

    go.drugbank.com/drugs/DB17033
    Experimental

    An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.

    Synonyms: Benzamide, n-(4-amino-2-methyl-6-quinolinyl)-2-((4-ethylphenoxy)methyl)-Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    NSC-663284

    go.drugbank.com/drugs/DB17038
    Experimental

    NSC-663284 is a potent quinolinedione Cdc25 phosphatase inhibitor.[A253052]

    Synonyms: 5,8-quinolinedione, 6-chloro-7-((2-(4-morpholinyl)ethyl)amino)-, 6-chloro-7-((2-morpholinoethyl)amino)quinoline-5,8-dioneCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    PI-103

    go.drugbank.com/drugs/DB17046
    Experimental

    PI-103 is an inhibitor of p110α of class I PI3K.[A253092]

    Synonyms: Phenol, 3-(4-(4-morpholinyl)pyrido(3',2':4,5)furo(3,2-d)pyrimidin-2-yl)-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    PIK-75

    go.drugbank.com/drugs/DB17047
    Experimental

    PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097]

    Synonyms: Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazideCategories: Phosphatidylinositol 3-Kinases, antagonists & inhibitors
  10. Drug

    Plumbagin

    go.drugbank.com/drugs/DB17048
    Investigational

    Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]

    Synonyms: 5-hydroxy-2-methyl-1,4-naphthalenedioneCategories: Compounds used in a research, industrial, or household setting